Gene Review:
toxA - exotoxin A
Pseudomonas aeruginosa PAO1
- Secretion of toxin A from Pseudomonas aeruginosa PAO1, PAK, and PA103 by Escherichia coli. Hamood, A.N., Wick, M.J., Iglewski, B.H. Infect. Immun. (1990)
- Regulation of toxA and regA by the Escherichia coli fur gene and identification of a Fur homologue in Pseudomonas aeruginosa PA103 and PA01. Prince, R.W., Storey, D.G., Vasil, A.I., Vasil, M.L. Mol. Microbiol. (1991)
- Common virulence factors for bacterial pathogenicity in plants and animals. Rahme, L.G., Stevens, E.J., Wolfort, S.F., Shao, J., Tompkins, R.G., Ausubel, F.M. Science (1995)
- PtxR modulates the expression of QS-controlled virulence factors in the Pseudomonas aeruginosa strain PAO1. Carty, N.L., Layland, N., Colmer-Hamood, J.A., Calfee, M.W., Pesci, E.C., Hamood, A.N. Mol. Microbiol. (2006)
- Isolation and characterization of a Pseudomonas aeruginosa gene, ptxR, which positively regulates exotoxin A production. Hamood, A.N., Colmer, J.A., Ochsner, U.A., Vasil, M.L. Mol. Microbiol. (1996)
- Exotoxin A production in Pseudomonas aeruginosa requires the iron-regulated pvdS gene encoding an alternative sigma factor. Ochsner, U.A., Johnson, Z., Lamont, I.L., Cunliffe, H.E., Vasil, M.L. Mol. Microbiol. (1996)
- Linker insertion scanning of regA, an activator of exotoxin A production in Pseudomonas aeruginosa. Raivio, T.L., Hoffer, D., Prince, R.W., Vasil, M.L., Storey, D.G. Mol. Microbiol. (1996)
- Characterization of Pseudomonas aeruginosa mutants that are deficient in exotoxin A synthesis and are altered in expression of regA, a positive regulator of exotoxin A. West, S.E., Kaye, S.A., Hamood, A.N., Iglewski, B.H. Infect. Immun. (1994)
- Effect of regB on expression from the P1 and P2 promoters of the Pseudomonas aeruginosa regAB operon. Storey, D.G., Raivio, T.L., Frank, D.W., Wick, M.J., Kaye, S., Iglewski, B.H. J. Bacteriol. (1991)
- Possible insertion sequences in a mosaic genome organization upstream of the exotoxin A gene in Pseudomonas aeruginosa. Pritchard, A.E., Vasil, M.L. J. Bacteriol. (1990)
- Genetic rearrangement associated with in vivo mucoid conversion of Pseudomonas aeruginosa PAO is due to insertion elements. Sokol, P.A., Luan, M.Z., Storey, D.G., Thirukkumaran, P. J. Bacteriol. (1994)
- Population transcript accumulation of Pseudomonas aeruginosa exotoxin A and elastase in sputa from patients with cystic fibrosis. Storey, D.G., Ujack, E.E., Rabin, H.R. Infect. Immun. (1992)
- Ferric uptake regulator mutants of Pseudomonas aeruginosa with distinct alterations in the iron-dependent repression of exotoxin A and siderophores in aerobic and microaerobic environments. Barton, H.A., Johnson, Z., Cox, C.D., Vasil, A.I., Vasil, M.L. Mol. Microbiol. (1996)
- The oxygen- and iron-dependent sigma factor pvdS of Pseudomonas aeruginosa is an important virulence factor in experimental infective endocarditis. Xiong, Y.Q., Vasil, M.L., Johnson, Z., Ochsner, U.A., Bayer, A.S. J. Infect. Dis. (2000)
- Physiological characterization of Pseudomonas aeruginosa during exotoxin A synthesis: glutamate, iron limitation, and aconitase activity. Somerville, G., Mikoryak, C.A., Reitzer, L. J. Bacteriol. (1999)
- Positive correlation of algD transcription to lasB and lasA transcription by populations of Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis. Storey, D.G., Ujack, E.E., Mitchell, I., Rabin, H.R. Infect. Immun. (1997)
- ToxR (RegA)-mediated in vitro transcription of Pseudomonas aeruginosa toxA. Walker, S.L., Hiremath, L.S., Wozniak, D.J., Galloway, D.R. Gene (1994)
- Characterization of DNA-binding specificity and analysis of binding sites of the Pseudomonas aeruginosa global regulator, Vfr, a homologue of the Escherichia coli cAMP receptor protein. Kanack, K.J., Runyen-Janecky, L.J., Ferrell, E.P., Suh, S.J., West, S.E. Microbiology (Reading, Engl.) (2006)
- Transcriptional analysis of the Pseudomonas aeruginosa toxA regulatory gene ptxR. Colmer-Hamood, J.A., Aramaki, H., Gaines, J.M., Hamood, A.N. Can. J. Microbiol. (2006)
- Nucleotide sequence and characterization of toxR: a gene involved in exotoxin A regulation in Pseudomonas aeruginosa. Wozniak, D.J., Cram, D.C., Daniels, C.J., Galloway, D.R. Nucleic Acids Res. (1987)
- Gradient of genomic diversity in the Pseudomonas aeruginosa chromosome. Römling, U., Greipel, J., Tümmler, B. Mol. Microbiol. (1995)
- Discriminatory power of three DNA-based typing techniques for Pseudomonas aeruginosa. Grundmann, H., Schneider, C., Hartung, D., Daschner, F.D., Pitt, T.L. J. Clin. Microbiol. (1995)
- Development of a multilocus sequence typing scheme for the opportunistic pathogen Pseudomonas aeruginosa. Curran, B., Jonas, D., Grundmann, H., Pitt, T., Dowson, C.G. J. Clin. Microbiol. (2004)
- Toxin A secretion in Pseudomonas aeruginosa: the role of the first 30 amino acids of the mature toxin. McVay, C.S., Hamood, A.N. Mol. Gen. Genet. (1995)
- Regulation of toxA by PtxR in Pseudomonas aeruginosa PA103. Carty, N.L., Rumbaugh, K.P., Hamood, A.N. Can. J. Microbiol. (2003)
- Expression of ptxR and its effect on toxA and regA expression during the growth cycle of Pseudomonas aeruginosa strain PAO1. Colmer, J.A., Hamood, A.N. Can. J. Microbiol. (1999)