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Gene Review

EPSTI1  -  epithelial stromal interaction 1 (breast)

Homo sapiens

Synonyms: BRESI1, Epithelial-stromal interaction protein 1, MGC29634
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Disease relevance of EPSTI1

  • 3. EPSTI1 was highly upregulated in invasive breast carcinomas compared with normal breast [1].
  • Identification of EPSTI1, a novel gene induced by epithelial-stromal interaction in human breast cancer [1].
  • Thus, EPSTI1 is a novel human gene expressed in tissues characterized by extensive epithelial-stromal interaction, and expression of this gene may be a crucial event in invasion and metastasis of cancer [1].

High impact information on EPSTI1


  1. Identification of EPSTI1, a novel gene induced by epithelial-stromal interaction in human breast cancer. Nielsen, H.L., Rønnov-Jessen, L., Villadsen, R., Petersen, O.W. Genomics (2002) [Pubmed]
  2. To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia. Gudjonsson, T., Rønnov-Jessen, L., Villadsen, R., Bissell, M.J., Petersen, O.W. Methods (2003) [Pubmed]
  3. Isolation and expression profiling of genes upregulated in the peripheral blood cells of systemic lupus erythematosus patients. Ishii, T., Onda, H., Tanigawa, A., Ohshima, S., Fujiwara, H., Mima, T., Katada, Y., Deguchi, H., Suemura, M., Miyake, T., Miyatake, K., Kawase, I., Zhao, H., Tomiyama, Y., Saeki, Y., Nojima, H. DNA Res. (2005) [Pubmed]
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