Disease relevance of fucA

• The order of the fucA, -P, -I, and -K genes was the same in the two E. coli strains [1].
• Upon consideration of the transductional nature of these phage classes, we are proposing that the gene order for the L-fucose utilization system is dar, fucA, (lambda), fucC [2].

High impact information on fucA

• The mutation that confers on the organism the ability to take up fructose via the fucose regulon was located as a deletion of the fucA gene with consequent induction of the proton-linked fucose transporter, FucP [3].
• However, the E. coli B gene cluster contained a 5.2-kb segment located between the fucA and fucP genes that was not present in E. coli K-12 [1].
• In the present study, we show that fucO and fucA form an operon which is divergently transcribed from the adjacent fucPIK operon [4].
• The fuc genes belong to a regulon comprising four linked operons: fucO, fucA, fucPIK, and fucR [5].
• One carried the markers argA and fucA (a fucose utilization gene of unknown function previously referred to as fuc-1) and the gene for D-arabinose utilization (dar+) [2].

Chemical compound and disease context of fucA

• The synthesis of propanediol oxidoreductase, an enzyme permitting the anaerobic metabolism of fucose and rhamnose, has been described as being controlled by the prd locus closely linked to the fuc locus in wild-type cells of Escherichia coli [6].

Biological context of fucA

• The fucPIK and fucA operons are transcribed clockwise [7].

References