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Gene Review

MED13  -  mediator complex subunit 13

Homo sapiens

Synonyms: ARC250, Activator-recruited cofactor 250 kDa component, DRIP250, HSPC221, KIAA0593, ...
 
 
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Disease relevance of THRAP1

 

High impact information on THRAP1

 

Biological context of THRAP1

 

Anatomical context of THRAP1

 

Physical interactions of THRAP1

 

Other interactions of THRAP1

References

  1. Missense mutations and gene interruption in PROSIT240, a novel TRAP240-like gene, in patients with congenital heart defect (transposition of the great arteries). Muncke, N., Jung, C., Rüdiger, H., Ulmer, H., Roeth, R., Hubert, A., Goldmuntz, E., Driscoll, D., Goodship, J., Schön, K., Rappold, G. Circulation (2003) [Pubmed]
  2. Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. Ge, K., Guermah, M., Yuan, C.X., Ito, M., Wallberg, A.E., Spiegelman, B.M., Roeder, R.G. Nature (2002) [Pubmed]
  3. Thyroid hormone receptor-associated proteins and general positive cofactors mediate thyroid hormone receptor function in the absence of the TATA box-binding protein-associated factors of TFIID. Fondell, J.D., Guermah, M., Malik, S., Roeder, R.G. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  4. Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. Fondell, J.D., Ge, H., Roeder, R.G. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  5. Phosphorylation of Thyroid Hormone Receptor-associated Nuclear Receptor Corepressor Holocomplex by the DNA-dependent Protein Kinase Enhances Its Histone Deacetylase Activity. Jeyakumar, M., Liu, X.F., Erdjument-Bromage, H., Tempst, P., Bagchi, M.K. J. Biol. Chem. (2007) [Pubmed]
  6. A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression. Wang, Q., Sharma, D., Ren, Y., Fondell, J.D. J. Biol. Chem. (2002) [Pubmed]
  7. Decreased expression of thyroid receptor-associated protein 220 in temporal lobe tissue of patients with refractory epilepsy. Li, J.M., Wang, X.F., Xi, Z.Q., Gong, Y., Liu, F.Y., Sun, J.J., Wu, Y., Luan, G.M., Wang, Y.P., Li, Y.L., Zhang, J.G., Lu, Y., Li, H.W. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  8. Identification of mouse TRAP100: a transcriptional coregulatory factor for thyroid hormone and vitamin D receptors. Zhang, J., Fondell, J.D. Mol. Endocrinol. (1999) [Pubmed]
  9. SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex. Zhou, R., Bonneaud, N., Yuan, C.X., de Santa Barbara, P., Boizet, B., Schomber, T., Scherer, G., Roeder, R.G., Poulat, F., Berta, P., Tibor, S. Nucleic Acids Res. (2002) [Pubmed]
  10. Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones. Clark, J., Edwards, S., John, M., Flohr, P., Gordon, T., Maillard, K., Giddings, I., Brown, C., Bagherzadeh, A., Campbell, C., Shipley, J., Wooster, R., Cooper, C.S. Genes Chromosomes Cancer (2002) [Pubmed]
  11. Differential display RT-PCR analysis of human choriocarcinoma cell lines and normal term trophoblast cells: identification of new genes expressed in placenta. García, J., Castrillo, J.L. Placenta (2004) [Pubmed]
 
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