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MeSH Review

Myofascial Pain Syndromes

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Disease relevance of Myofascial Pain Syndromes


High impact information on Myofascial Pain Syndromes


Chemical compound and disease context of Myofascial Pain Syndromes

  • The results support the assumption that a dysfunctional end plate exhibiting increased release of ACh may be the starting point for regional abnormal contractions, which are thought to be essential for the formation of myofascial trigger points [11].
  • There are, however, no data on the efficacy of clonazepam for chronic pain (CP) associated with myofascial pain syndrome (MFPS) [5].
  • The effects of infrared laser and medical treatments on pain and serotonin degradation products in patients with myofascial pain syndrome. A controlled trial [12].

Biological context of Myofascial Pain Syndromes


Anatomical context of Myofascial Pain Syndromes


Gene context of Myofascial Pain Syndromes

  • RESULTS: The FREMS group showed a significant improvement in the NPDVAS, algometry, in myofascial trigger point characteristics, and in the ROM (homolateral rotation, controlateral rotation, bending and extension) after the end of treatment and at 1 and 3 months follow-up evaluation [13].
  • OBJECTIVES: After it had been proven that systemic application of the 5-HT3 receptor antagonist tropisetron exerts an analgesic effect on musculoskeletal pain in fibromyalgia, we investigated the efficacy of the substance in tendinopathies and myofascial pain syndromes [10].


  1. A comparative trial of botulinum toxin type A and methylprednisolone for the treatment of myofascial pain syndrome and pain from chronic muscle spasm. Porta, M. Pain (2000) [Pubmed]
  2. Neurobiological basis for the use of botulinum toxin in pain therapy. Mense, S. J. Neurol. (2004) [Pubmed]
  3. Clinical study of chronic pain in hereditary myopathies. Delorme, T., Boureau, F., Eymard, B., Laforet, P., Cottrel, F. European journal of pain (London, England) (2004) [Pubmed]
  4. Treatment of chronic low back pain with tropisetron. Stratz, T., Müller, W. Scand. J. Rheumatol. Suppl. (2004) [Pubmed]
  5. Clonazepam open clinical treatment trial for myofascial syndrome associated chronic pain. Fishbain, D.A., Cutler, R.B., Rosomoff, H.L., Rosomoff, R.S. Pain medicine (Malden, Mass.) (2000) [Pubmed]
  6. Botulinum toxin A versus bupivacaine trigger point injections for the treatment of myofascial pain syndrome: a randomised double blind crossover study. Graboski, C.L., Gray, D.S., Burnham, R.S. Pain (2005) [Pubmed]
  7. The superiority of water-diluted 0.25% to neat 1% lidocaine for trigger-point injections in myofascial pain syndrome: a prospective, randomized, double-blinded trial. Iwama, H., Akama, Y. Anesth. Analg. (2000) [Pubmed]
  8. Botulinum toxin type A as a migraine preventive treatment. For the BOTOX Migraine Clinical Research Group. Silberstein, S., Mathew, N., Saper, J., Jenkins, S. Headache. (2000) [Pubmed]
  9. Myofascial pain syndromes: where are we? Where are we going? Simons, D.G. Archives of physical medicine and rehabilitation. (1988) [Pubmed]
  10. Local treatment of tendinopathies and myofascial pain syndromes with the 5-HT3 receptor antagonist tropisetron. Müller, W., Stratz, T. Scand. J. Rheumatol. Suppl. (2004) [Pubmed]
  11. Lesions of rat skeletal muscle after local block of acetylcholinesterase and neuromuscular stimulation. Mense, S., Simons, D.G., Hoheisel, U., Quenzer, B. J. Appl. Physiol. (2003) [Pubmed]
  12. The effects of infrared laser and medical treatments on pain and serotonin degradation products in patients with myofascial pain syndrome. A controlled trial. Ceylan, Y., Hizmetli, S., Siliğ, Y. Rheumatol. Int. (2004) [Pubmed]
  13. A randomized controlled study on the effect of two different treatments (FREMS AND TENS) in myofascial pain syndrome. Farina, S., Casarotto, M., Benelle, M., Tinazzi, M., Fiaschi, A., Goldoni, M., Smania, N. Europa medicophysica. (2004) [Pubmed]
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