Disease relevance of Neck Pain

• The Neck Disability Index (NDI) and Northwick Park Neck Pain Questionnaire (NPQ) were developed to measure self-perceived disability from neck pain, including that which may arise from whiplash injury [1].
• A 34-year-old woman with Factor XI deficiency presented with rapidly progressive quadriplegia following a 1-week prodrome of cervical pain [2].
• Twenty-one with symptomatic cervical spondylosis or nonspecific neck pain were given an amnesic dose of diazepam before manipulation of the cervical spine [3].
• In both horses, the joint infections resolved after i.v. administration of amphotericin B and joint drainage; however, 1 horse was eventually euthanatized because of signs of cervical pain and progressively worsening ataxia [4].
• She was diagnosed as having Graves' disease and was treated with propylthiouracil, and prednisolone was given for neck pain [5].

High impact information on Neck Pain

• The primary outcome was the Northwick Park Neck Pain Questionnaire [6].
• The occurrence of neck pain at least once a month was 21.3 and 43.4% and at least once a week was 6.3 and 19.4% [7].
• Patients were compared for 4 months using a comprehensive set of outcome measures that included the Neck Pain and Disability Scale (Spine 24 (1999) 1290) and pressure algometry (Arch Phys Med Rehabil 67 (1986) 406; Pain 30 (1987) 115; Clin J Pain 2 (1987) 207) [8].
• Chronic neck pain. American College of Radiology. ACR Appropriateness Criteria [9].
• In an ascending method of limits design. electrical stimuli at 100 Hz with variation in current from 0 to 45 mA and in pulse width from 100 to 1000 micros were delivered transcutaneously to two points 2 cm from the midline bilaterally at the levels of C5/6 and C7/T1 in 35 subjects with chronic neck pain and 22 pain-free volunteers [10].

Chemical compound and disease context of Neck Pain

• The diagnosis of third occipital nerve headache was made only if both blocks completely relieved the patient's upper neck pain and headache and the relief lasted longer with bupivacaine [11].
• Feedforward activity of the cervical flexor muscles during voluntary arm movements is delayed in chronic neck pain [12].
• In chronic MND with radicular findings, epidural methylprednisolone and lidocaine reduced neck pain [SMD -1.46 (95% CI -2.16 to -0.76)] and improved function at one-year followup compared to the intramuscular route [13].
• In conclusion, succinylcholine contributes to neck pain and muscle stiffness after laparoscopic procedures [14].
• Only neck pain was more common with iopamidol [15].

Biological context of Neck Pain

• Patients with VAD complained more often of neck pain, more frequently reported a preceding chiropractic manipulation and had a higher incidence of bilateral dissections than patients with CAD [16].
• An endurance-strength training regime is effective in reducing myoelectric manifestations of cervical flexor muscle fatigue in females with chronic neck pain [17].
• CONCLUSIONS: Stress-induced shoulder and neck pain is not necessarily associated with elevated trapezius muscle activity, but pain-free workers may benefit from better muscle relaxation in leisure [18].
• The study investigates the outcome of acupuncture for chronic neck pain in a cohort of patients referred to an NHS chronic pain clinic [19].

Anatomical context of Neck Pain

• OBJECTIVES: To compare the isometric neck muscle strength of cervical dystonia patients treated with botulinum toxin injections with that of healthy control subjects and to evaluate the association between neck strength, neck pain, and disability in these patients [20].
• CONCLUSION: Hand-assisted laparoscopy is associated with more frequent neuromuscular strain to the upper extremity than SL, but SL surgeons experience more neck pain or injury [21].
• A functional convergence of sensorimotor fibers in the spinal accessory nerve (CN XI) and upper cervical nerve roots ultimately converge with the descending tract of the trigeminal nerve and might also be responsible for the referral of cervical pain to the head [22].
• In patients with systemic lupus erythematosus who present with fever and anterior neck pain, infection of the thyroid gland should be considered, and appropriate investigations undertaken [23].
• The literature reports evidence of various types of correlations between cervical alterations and cervical pain, and the existence of cervical pain in subjects with temporomandibular joint internal derangement (TMD) [24].

Gene context of Neck Pain

• Targeted etanercept for discogenic neck pain: uncontrolled, open-label results in two adults [25].
• METHODS: The presence of symptoms in the emergency room (ER) (headache, dizziness, nausea, vomiting, and neck pain) and biochemical markers (neurone specific enolase and S-100B) in serum were assessed as possible predictive variables for the severity of PTC [26].
• METHODS: Anteroposterior and lateral weight-bearing radiographs were obtained of 308 feet of patients with RA and 202 feet of patients with neck pain (control feet) [27].
• Here we assess the capability of 10 cervical dystonia patients, 5 patients with cervical pain but no dystonia, and 10 healthy controls to determine whether pairs of visual, tactile or visuo-tactile stimuli were simultaneous or sequential (TD threshold) and which stimulus preceded the other (temporal order judgement, TOJ) [28].
• An AOA critical issue. Disc replacements: this time will we really cure low-back and neck pain [29]?

Analytical, diagnostic and therapeutic context of Neck Pain

• CONCLUSION: Neck dissections sparing CN XI are associated with better pain scores on the HNQOL, less shoulder and neck pain, and less need for medications [30].
• Spanish version of the Northwick Park Neck Pain Questionnaire: reliability and validity [31].
• Pain visual analogue scale (VAS), the short-form McGill pain and Northwick Park neck pain questionnaires were completed before, midway and after the treatment period [32].
• CLINICAL FEATURES: A 35-year-old woman had chronic neck pain for over 5 years after two separate surgeries of the cervical spine: a diskectomy at C3/4 and a fusion at C5/6 [33].
• The second most frequent side effect was neck pain; the duration of neck pain were significantly longer after myelography with iohexol than with iotrolan [34].

References