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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Neck Pain

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Disease relevance of Neck Pain


High impact information on Neck Pain

  • The primary outcome was the Northwick Park Neck Pain Questionnaire [6].
  • The occurrence of neck pain at least once a month was 21.3 and 43.4% and at least once a week was 6.3 and 19.4% [7].
  • Patients were compared for 4 months using a comprehensive set of outcome measures that included the Neck Pain and Disability Scale (Spine 24 (1999) 1290) and pressure algometry (Arch Phys Med Rehabil 67 (1986) 406; Pain 30 (1987) 115; Clin J Pain 2 (1987) 207) [8].
  • Chronic neck pain. American College of Radiology. ACR Appropriateness Criteria [9].
  • In an ascending method of limits design. electrical stimuli at 100 Hz with variation in current from 0 to 45 mA and in pulse width from 100 to 1000 micros were delivered transcutaneously to two points 2 cm from the midline bilaterally at the levels of C5/6 and C7/T1 in 35 subjects with chronic neck pain and 22 pain-free volunteers [10].

Chemical compound and disease context of Neck Pain

  • The diagnosis of third occipital nerve headache was made only if both blocks completely relieved the patient's upper neck pain and headache and the relief lasted longer with bupivacaine [11].
  • Feedforward activity of the cervical flexor muscles during voluntary arm movements is delayed in chronic neck pain [12].
  • In chronic MND with radicular findings, epidural methylprednisolone and lidocaine reduced neck pain [SMD -1.46 (95% CI -2.16 to -0.76)] and improved function at one-year followup compared to the intramuscular route [13].
  • In conclusion, succinylcholine contributes to neck pain and muscle stiffness after laparoscopic procedures [14].
  • Only neck pain was more common with iopamidol [15].

Biological context of Neck Pain


Anatomical context of Neck Pain


Gene context of Neck Pain

  • Targeted etanercept for discogenic neck pain: uncontrolled, open-label results in two adults [25].
  • METHODS: The presence of symptoms in the emergency room (ER) (headache, dizziness, nausea, vomiting, and neck pain) and biochemical markers (neurone specific enolase and S-100B) in serum were assessed as possible predictive variables for the severity of PTC [26].
  • METHODS: Anteroposterior and lateral weight-bearing radiographs were obtained of 308 feet of patients with RA and 202 feet of patients with neck pain (control feet) [27].
  • Here we assess the capability of 10 cervical dystonia patients, 5 patients with cervical pain but no dystonia, and 10 healthy controls to determine whether pairs of visual, tactile or visuo-tactile stimuli were simultaneous or sequential (TD threshold) and which stimulus preceded the other (temporal order judgement, TOJ) [28].
  • An AOA critical issue. Disc replacements: this time will we really cure low-back and neck pain [29]?

Analytical, diagnostic and therapeutic context of Neck Pain


  1. Validity of the neck disability index, Northwick Park neck pain questionnaire, and problem elicitation technique for measuring disability associated with whiplash-associated disorders. Hoving, J.L., O'Leary, E.F., Niere, K.R., Green, S., Buchbinder, R. Pain (2003) [Pubmed]
  2. Spontaneous hematomyelia secondary to factor XI deficiency. Case report. Wisoff, J.H., Rovit, R.L., Ho, V., Leventhal, H. J. Neurosurg. (1985) [Pubmed]
  3. Manipulation for chronic neck pain. A double-blind controlled study. Sloop, P.R., Smith, D.S., Goldenberg, E., Doré, C. Spine. (1982) [Pubmed]
  4. Amphotericin B treatment of Candida arthritis in two horses. Madison, J.B., Reid, B.V., Raskin, R.E. J. Am. Vet. Med. Assoc. (1995) [Pubmed]
  5. Graves' disease presented as painful goiter. Chao, C.S., Lin, S.Y., Sheu, W.H. Horm. Res. (2002) [Pubmed]
  6. Effectiveness of manual therapy or pulsed shortwave diathermy in addition to advice and exercise for neck disorders: a pragmatic randomized controlled trial in physical therapy clinics. Dziedzic, K., Hill, J., Lewis, M., Sim, J., Daniels, J., Hay, E.M. Arthritis Rheum. (2005) [Pubmed]
  7. Neck pain in adolescence. A 4-year follow-up of pain-free preadolescents. Ståhl, M., Mikkelsson, M., Kautiainen, H., Häkkinen, A., Ylinen, J., Salminen, J.J. Pain (2004) [Pubmed]
  8. Botulinum toxin A for the treatment of chronic neck pain. Wheeler, A.H., Goolkasian, P., Gretz, S.S. Pain (2001) [Pubmed]
  9. Chronic neck pain. American College of Radiology. ACR Appropriateness Criteria. Daffner, R.H., Dalinka, M.K., Alazraki, N., Berquist, T.H., DeSmet, A.A., el-Khoury, G.Y., Goergen, T.G., Keats, T.E., Manaster, B.J., Newberg, A., Pavlov, H., Schweitzer, M.E., Haralson, R.H., McCabe, J.B. Radiology. (2000) [Pubmed]
  10. Psychophysical evidence for a neuropathic component of chronic neck pain. Sheather-Reid, R.B., Cohen, M.L. Pain (1998) [Pubmed]
  11. Third occipital nerve headache: a prevalence study. Lord, S.M., Barnsley, L., Wallis, B.J., Bogduk, N. J. Neurol. Neurosurg. Psychiatr. (1994) [Pubmed]
  12. Feedforward activity of the cervical flexor muscles during voluntary arm movements is delayed in chronic neck pain. Falla, D., Jull, G., Hodges, P.W. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (2004) [Pubmed]
  13. Medicinal and injection therapies for mechanical neck disorders: a cochrane systematic review. Peloso, P.M., Gross, A.R., Haines, T.A., Trinh, K., Goldsmith, C.H., Aker, P. J. Rheumatol. (2006) [Pubmed]
  14. Muscle pain after outpatient laparoscopy--influence of propofol versus thiopental and enflurane. Smith, I., Ding, Y., White, P.F. Anesth. Analg. (1993) [Pubmed]
  15. Iopamidol vs. metrizamide myelography: clinical comparison of side effects. Trevisan, C., Malaguti, C., Manfredini, M., Tampieri, D. AJNR. American journal of neuroradiology. (1983) [Pubmed]
  16. Cervical artery dissection--clinical features, risk factors, therapy and outcome in 126 patients. Dziewas, R., Konrad, C., Dräger, B., Evers, S., Besselmann, M., Lüdemann, P., Kuhlenbäumer, G., Stögbauer, F., Ringelstein, E.B. J. Neurol. (2003) [Pubmed]
  17. An endurance-strength training regime is effective in reducing myoelectric manifestations of cervical flexor muscle fatigue in females with chronic neck pain. Falla, D., Jull, G., Hodges, P., Vicenzino, B. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. (2006) [Pubmed]
  18. Daytime trapezius muscle activity and shoulder-neck pain of service workers with work stress and low biomechanical exposure. Holte, K.A., Westgaard, R.H. Am. J. Ind. Med. (2002) [Pubmed]
  19. Acupuncture for chronic neck pain--a cohort study in an NHS pain clinic. Blossfeldt, P. Acupuncture in medicine : journal of the British Medical Acupuncture Society. (2004) [Pubmed]
  20. Decreased neck muscle strength is highly associated with pain in cervical dystonia patients treated with botulinum toxin injections. Häkkinen, A., Ylinen, J., Rinta-Keturi, M., Talvitie, U., Kautiainen, H., Rissanen, A. Archives of physical medicine and rehabilitation. (2004) [Pubmed]
  21. Comparison of neuromuscular injuries to the surgeon during hand-assisted and standard laparoscopic urologic surgery. Johnston, W.K., Hollenbeck, B.K., Wolf, J.S. J. Endourol. (2005) [Pubmed]
  22. Cervicogenic headache: a review of diagnostic and treatment strategies. Biondi, D.M. The Journal of the American Osteopathic Association. (2005) [Pubmed]
  23. Infective thyroiditis in two cases of systemic lupus erythematosus. Fung, L.M., Ma, R.C., Chow, C.C., Cockram, C.S. Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine. (2004) [Pubmed]
  24. Cervical lordosis angle measured on lateral cephalograms; findings in skeletal class II female subjects with and without TMD: a cross sectional study. D'Attilio, M., Epifania, E., Ciuffolo, F., Salini, V., Filippi, M.R., Dolci, M., Festa, F., Tecco, S. Cranio : the journal of craniomandibular practice. (2004) [Pubmed]
  25. Targeted etanercept for discogenic neck pain: uncontrolled, open-label results in two adults. Tobinick, E.L. Clinical therapeutics. (2003) [Pubmed]
  26. Prediction of post-traumatic complaints after mild traumatic brain injury: early symptoms and biochemical markers. De Kruijk, J.R., Leffers, P., Menheere, P.P., Meerhoff, S., Rutten, J., Twijnstra, A. J. Neurol. Neurosurg. Psychiatr. (2002) [Pubmed]
  27. Rheumatoid flat foot and deformity of the first ray. Bouysset, M., Tebib, J., Noel, E., Tavernier, T., Miossec, P., Vianey, J.C., Duivon, J.P., Bonnin, M., Nemoz, C., Jalby, J. J. Rheumatol. (2002) [Pubmed]
  28. Timing of tactile and visuo-tactile events is impaired in patients with cervical dystonia. Tinazzi, M., Fiorio, M., Bertolasi, L., Aglioti, S.M. J. Neurol. (2004) [Pubmed]
  29. An AOA critical issue. Disc replacements: this time will we really cure low-back and neck pain? Boden, S.D., Balderston, R.A., Heller, J.G., Hanley, E.N., Zigler, J.E. The Journal of bone and joint surgery. American volume. (2004) [Pubmed]
  30. Pain, quality of life, and spinal accessory nerve status after neck dissection. Terrell, J.E., Welsh, D.E., Bradford, C.R., Chepeha, D.B., Esclamado, R.M., Hogikyan, N.D., Wolf, G.T. Laryngoscope (2000) [Pubmed]
  31. Spanish version of the Northwick Park Neck Pain Questionnaire: reliability and validity. González, T., Balsa, A., Sáinz de Murieta, J., Zamorano, E., González, I., Martin-Mola, E. Clinical and experimental rheumatology. (2001) [Pubmed]
  32. A randomized clinical trial of manual therapy for cervico-brachial pain syndrome -- a pilot study. Allison, G.T., Nagy, B.M., Hall, T. Manual therapy. (2002) [Pubmed]
  33. Chiropractic treatment of postsurgical neck syndrome with mechanical force, manually assisted short-lever spinal adjustments. Polkinghorn, B.S., Colloca, C.J. Journal of manipulative and physiological therapeutics. (2001) [Pubmed]
  34. A prospective comparison of iotrolan and iohexol in lumbar myelography. Wagner, A., Jensen, C., Saebye, A., Rasmussen, T.B. Acta radiologica (Stockholm, Sweden : 1987) (1994) [Pubmed]
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