Disease relevance of Median Neuropathy

• Sixty-five patients (29%) had a peripheral nerve disorder; 27 had symptoms of thoracic outlet syndrome; 12 had median neuropathies (carpal tunnel syndrome in 9); 9 had ulnar neuropathies; 6 had cervical radiculopathy; 5 had digital neuropathies; 3 had cranial neuropathies; and 3 had other peripheral nerve disorders [1].
• A 27-year-old male patient, a machinist, had median neuropathy after a minor contusion on his right wrist and underwent carpal tunnel release under the impression of carpal tunnel syndrome five years ago [2].

High impact information on Median Neuropathy

• MAIN OUTCOME MEASURES: Population prevalence rates, calculated as the number of symptomatic responders diagnosed on examination as having clinically certain CTS and/or electrophysiological median neuropathy divided by the total number of responders [3].
• The difference between the motor latencies to the median-innervated second lumbrical (2L) and ulnar-innervated palmar interosseous (Pl) (Diff 2L-Pl) has been shown to be of localizing value in patients with median neuropathy at the wrist [4].
• Documentation shows that the first surgical division of the flexor retinaculum for treatment of distal median neuropathy was performed in 1924, almost a decade earlier than previously thought [5].
• Nerve conduction velocities revealed bilateral median neuropathy consistent with carpal tunnel syndrome (CTS) [6].

Biological context of Median Neuropathy

• Surface recording of the AINL could differentiate severe CTS with UMNDC, or with slow median motor nerve conduction velocity at the forearm, from median neuropathy or proximal compression [7].

References