Disease relevance of Cranial Nerve Diseases

• CARD15 mutations in familial granulomatosis syndromes: a study of the original Blau syndrome kindred and other families with large-vessel arteritis and cranial neuropathy [1].
• The authors report two North American patients with this disease who manifest blepharochalasis, lattice corneal dystrophy, open-angle glaucoma, and cranial neuropathy [2].
• PATIENTS AND METHODS: The study was a controlled clinical trial at two tertiary care centres of patients with SLE according to the ACR criteria, with incident (no more than 15 days) onset of severe NP manifestations such as seizures, optic neuritis, peripheral or cranial neuropathy, coma, brainstem disease, or transverse myelitis [3].
• Familial amyloidosis, Finnish type, is clinically characterized by cranial neuropathy and lattice corneal dystrophy [4].
• This report indicates that Ara-C neurotoxicity, possibly aggravated in our patient by oliguric renal failure, is not confined to the cerebellum but involves cranial nerve and spinal motor neurons, which in turn may explain the cranial neuropathies that sometimes complicate the use of high-dose Ara-C therapy [5].

High impact information on Cranial Nerve Diseases

• This disease is characterized by a cranial neuropathy that cannot be explained solely by amyloid deposits [6].
• Regional subacute cranial neuropathies following internal carotid cisplatin infusion [7].
• Both patients developed transient cranial neuropathy shortly after treatment with 186Re-HEDP [8].
• Trichloroethylene cranial neuropathy: is it really a toxic neuropathy or does it activate latent herpes virus [9]?
• The mechanism of the cranial neuropathy associated with heavy exposure to trichloroethylene (or dichloroethylene) is unknown [9].

Chemical compound and disease context of Cranial Nerve Diseases

• Role of Blink Reflex in diagnosis of subclinical cranial neuropathy in Diabetic Mellitus type II [10].

Biological context of Cranial Nerve Diseases

• Repeatedly negative CSF cytologies and recovery of the cranial neuropathy obscured the diagnosis [11].

Gene context of Cranial Nerve Diseases

• Three cases of cranial neuropathy complicating chrysotherapy for rheumatoid arthritis are described [12].
• We have recently shown that in a Danish and a Czech family with a clinical syndrome similar to FAF, including corneal lattice dystrophy, cranial neuropathy and skin changes, the disease is caused by another mutation at the same position, namely 654G-T predicting a Try-for-Asp substitution at 187 in secreted gelsolin [13].
• The pathogenesis of cranial neuropathy in systemic lupus erythematosus and the unique presentation in this patient are discussed [14].
• Spontaneous intracranial hypotension with unique strabismus due to third and fourth cranial neuropathies [15].

References