The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Radiculopathy


Psychiatry related information on Radiculopathy


High impact information on Radiculopathy


Chemical compound and disease context of Radiculopathy


Biological context of Radiculopathy


Anatomical context of Radiculopathy


Gene context of Radiculopathy

  • IL-8 seems to participate in the pathomechanism of nerve root inflammation in lumbar disc herniations, which implies that it may be considered a target for therapeutic intervention [24].
  • These results suggest that COX-2 and inflammatory cytokines might play a causative role in the radiculopathy of LDH through upregulating PGE2 synthesis [25].
  • CONCLUSION: Among thoracolumbar junction disc herniations, T10-T11 and T11-T12 disc herniations were considered upper neuron disorders, T12-L1 disc herniations were considered lower neuron disorders, L1-L2 disc herniations were considered mild disorders of the cauda equina and radiculopathy, and L2-L3 disc herniations were considered radiculopathy [26].
  • Twenty-seven patients presented with myelopathy, twelve with myeloradiculopathy and six with radiculopathy. 'Total' configuration of OPLL was the most frequent (70%) [27].
  • Radiculopathy as a complication of ankylosing spondylitis [28].

Analytical, diagnostic and therapeutic context of Radiculopathy


  1. Transthyretin Leu12Pro is associated with systemic, neuropathic and leptomeningeal amyloidosis. Brett, M., Persey, M.R., Reilly, M.M., Revesz, T., Booth, D.R., Booth, S.E., Hawkins, P.N., Pepys, M.B., Morgan-Hughes, J.A. Brain (1999) [Pubmed]
  2. Central administration of methotrexate reduces mechanical allodynia in an animal model of radiculopathy/sciatica. Hashizume, H., Rutkowski, M.D., Weinstein, J.N., DeLeo, J.A. Pain (2000) [Pubmed]
  3. Cefotaxime vs penicillin G for acute neurologic manifestations in Lyme borreliosis. A prospective randomized study. Pfister, H.W., Preac-Mursic, V., Wilske, B., Einhäupl, K.M. Arch. Neurol. (1989) [Pubmed]
  4. Anterior cervical arthrodesis using DOC dynamic stabilization implant for improvement in sagittal angulation and controlled settling. Bose, B. J. Neurosurg. (2003) [Pubmed]
  5. Enhanced lumbar nerve roots in the spine without prior surgery: radiculitis or radicular veins? Lane, J.I., Koeller, K.K., Atkinson, J.L. AJNR. American journal of neuroradiology. (1994) [Pubmed]
  6. Treatment of chronic pain by epidural spinal cord stimulation: a 10-year experience. Kumar, K., Nath, R., Wyant, G.M. J. Neurosurg. (1991) [Pubmed]
  7. Demyelinating radiculopathy in the Kearns-Sayre syndrome: a clinicopathological study. Groothuis, D.R., Schulman, S., Wollman, R., Frey, J., Vick, N.A. Ann. Neurol. (1980) [Pubmed]
  8. Expression of neurotrophic factors in the dorsal root ganglion in a rat model of lumbar disc herniation. Obata, K., Tsujino, H., Yamanaka, H., Yi, D., Fukuoka, T., Hashimoto, N., Yonenobu, K., Yoshikawa, H., Noguchi, K. Pain (2002) [Pubmed]
  9. Cervical radiculopathy: computed tomography and myelography compared. Daniels, D.L., Grogan, J.P., Johansen, J.G., Meyer, G.A., Williams, A.L., Haughton, V.M. Radiology. (1984) [Pubmed]
  10. Subarachnoid dissemination of thoracic chordoma. Aleksic, S., Budzilovich, G.N., Nirmel, K., Ransohoff, J., Feigin, I. Arch. Neurol. (1979) [Pubmed]
  11. Serious complications related to regional anesthesia: results of a prospective survey in France. Auroy, Y., Narchi, P., Messiah, A., Litt, L., Rouvier, B., Samii, K. Anesthesiology (1997) [Pubmed]
  12. Dexamethasone in the management of symptoms due to herniated lumbar disc. Green, L.N. J. Neurol. Neurosurg. Psychiatr. (1975) [Pubmed]
  13. Cervical radiculopathy: open study on percutaneous periradicular foraminal steroid infiltration performed under CT control in 30 patients. Cyteval, C., Thomas, E., Decoux, E., Sarrabere, M.P., Cottin, A., Blotman, F., Taourel, P. AJNR. American journal of neuroradiology. (2004) [Pubmed]
  14. The human cervical myotomes: an anatomical correlation between electromyography and CT/myelography. Katirji, M.B., Agrawal, R., Kantra, T.A. Muscle Nerve (1988) [Pubmed]
  15. Minimally invasive lateral mass screws in the treatment of cervical facet dislocations: technical note. Wang, M.Y., Prusmack, C.J., Green, B.A., Gruen, J.P., Levi, A.D. Neurosurgery (2003) [Pubmed]
  16. Neuropharmacology of the dorsal root entry zone. Blumenkopf, B. Neurosurgery (1984) [Pubmed]
  17. Effects of diclofenac and ketoprofen on nerve conduction velocity in experimental nerve root compression. Cornefjord, M., Olmarker, K., Otani, K., Rydevik, B. Spine. (2001) [Pubmed]
  18. Segmental H-reflex studies in upper and lower limbs of patients with radiculopathy. Sabbahi, M.A., Khalil, M. Archives of physical medicine and rehabilitation. (1990) [Pubmed]
  19. Plasma and cerebrospinal fluid concentrations of paracetamol after a single intravenous dose of propacetamol. Bannwarth, B., Netter, P., Lapicque, F., Gillet, P., Péré, P., Boccard, E., Royer, R.J., Gaucher, A. British journal of clinical pharmacology. (1992) [Pubmed]
  20. Extradural tethering effect as one mechanism of radiculopathy complicating posterior decompression of the cervical spinal cord. Tsuzuki, N., Abe, R., Saiki, K., Zhongshi, L. Spine. (1996) [Pubmed]
  21. Aeolus myth: chronic obstructive lung disease and nocturnal lumbosacral pain in association with lumbar spinal stenosis and pulmonary hypertension. LaBan, M.M., Kucway, E.J. American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. (2003) [Pubmed]
  22. Reliability and diagnostic accuracy of the clinical examination and patient self-report measures for cervical radiculopathy. Wainner, R.S., Fritz, J.M., Irrgang, J.J., Boninger, M.L., Delitto, A., Allison, S. Spine. (2003) [Pubmed]
  23. Effect of lumbar nerve root compression on primary sensory neurons and their central branches: changes in the nociceptive neuropeptides substance P and somatostatin. Kobayashi, S., Kokubo, Y., Uchida, K., Yayama, T., Takeno, K., Negoro, K., Nakajima, H., Baba, H., Yoshizawa, H. Spine. (2005) [Pubmed]
  24. mRNA expression of cytokines and chemokines in herniated lumbar intervertebral discs. Ahn, S.H., Cho, Y.W., Ahn, M.W., Jang, S.H., Sohn, Y.K., Kim, H.S. Spine. (2002) [Pubmed]
  25. The role of cyclooxygenase-2 and inflammatory cytokines in pain induction of herniated lumbar intervertebral disc. Miyamoto, H., Saura, R., Harada, T., Doita, M., Mizuno, K. The Kobe journal of medical sciences. (2000) [Pubmed]
  26. Symptoms of thoracolumbar junction disc herniation. Tokuhashi, Y., Matsuzaki, H., Uematsu, Y., Oda, H. Spine. (2001) [Pubmed]
  27. Ossification of the posterior longitudinal ligament of the cervical spine in Asian Indians--a multiracial comparison. Jayakumar, P.N., Kolluri, V.R., Vasudev, M.K., Srikanth, S.G. Clinical neurology and neurosurgery. (1996) [Pubmed]
  28. Radiculopathy as a complication of ankylosing spondylitis. Cumming, W.J., Saunders, M. J. Neurol. Neurosurg. Psychiatr. (1978) [Pubmed]
  29. Roles of thromboxane A2 and leukotriene B4 in radicular pain induced by herniated nucleus pulposus. Kawakami, M., Matsumoto, T., Tamaki, T. J. Orthop. Res. (2001) [Pubmed]
  30. Cervical nerve root avulsion in brachial plexus injuries: magnetic resonance imaging classification and comparison with myelography and computerized tomography myelography. Doi, K., Otsuka, K., Okamoto, Y., Fujii, H., Hattori, Y., Baliarsing, A.S. J. Neurosurg. (2002) [Pubmed]
  31. High cervical disc herniation presenting with C-2 radiculopathy. Case report and review of the literature. Deshmukh, V.R., Rekate, H.L., Sonntag, V.K. J. Neurosurg. (2004) [Pubmed]
  32. Neuropeptide changes in compressed spinal nerve roots. Cornefjord, M., Olmarker, K., Farley, D.B., Weinstein, J.N., Rydevik, B. Spine. (1995) [Pubmed]
  33. The effect of cervical traction combined with conventional therapy on grip strength on patients with cervical radiculopathy. Joghataei, M.T., Arab, A.M., Khaksar, H. Clinical rehabilitation. (2004) [Pubmed]
WikiGenes - Universities