Disease relevance of Myrsinaceae

• New cyclopentenone derivatives from an endophytic Streptomyces sp. isolated from the mangrove plant Aegiceras comiculatum [1].

High impact information on Myrsinaceae

• Rapanone (2,5-dihydroxy-3-tridecyl-1,4-benzoquinone), a natural compound isolated from Myrsine guianensis growing in the Andean highlands of Colombia, was studied in different in vitro and in vivo models as a potential antioxidant and anti-inflammatory drug [2].
• Benzoquinone derivatives of Myrsine africana and Maesa lanceolata [3].
• Phospholipase D inhibitors from a Myrsine species [4].
• Toxicants from mangrove plants, V. Isolation of the piscicide, 2-hydroxy-5-methoxy-3-undecyl-1,4 benzoquinone (5-O-methylembelin) from Aegiceras corniculatum [5].
• A new oleanane triterpene, 16alpha-hydroxy-l3,28-epoxyoleanan-3-one 1, was isolated from the stem bark of Aegiceras corniculatum, together with protoprimulagenin, aegicerin, embelinone, syringic acid, gallic acid, isorhamnetin and isorhamnetin 3-O-alpha-L-rhamnofuranosyl-(1-->6)-beta-D-glucopyranoside [6].

Associations of Myrsinaceae with chemical compounds

• The methanolic extract of Myrsine seguinii yielded the novel anti-inflammatory compound, myrsinoic acid E (1), whose structure was elucidated to be 3,5-digeranyl-4-hydroxy benzoic acid [7].
• Bioassay-guided isolation of anti-inflammatory compounds from the methanol extract of Myrsine seguinii yielded an anti-inflammatory compound (1) [8].
• The hypoglycemic effect of Embelia madagascariensis (Myrsinaceae) was investigated in both normal and streptozotocin-induced diabetic mice [9].
• Compared to an untreated control group, the efficacy against nematodes was 77, 89.8 and 90% for Myrsine afriacana, Albizia antihelmintica and Hilderbrantia sepalosa, respectively, while albendazole had 100% efficacy [10].

References