Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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MeSH Review:

Rickettsia felis

Moron, C.G. et al., Higgins, J.A. et al., Blanc, G. et al., Blair, P.J. et al., Horta, M.C. et al., et al.

Eremeeva, Madan, Shaw, Tang, Dasch, Richter, Fournier, Petridou, Häussinger, Raoult, Blair, Jiang, Schoeler, Moron, Anaya, Cespedes, Cruz, Felices, Guevara, Mendoza, Villaseca, Sumner, Richards, Olson,

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Disease relevance of Rickettsia felis

We undertook sequencing and molecular analysis of the rompB gene of Rickettsia felis and a comparison with its homologs in spotted fever group (SFG) and typhus group (TG) rickettsiae, including the complete sequences of two North American flying squirrel strains and two European human strains of Rickettsia prowazekii [1].

High impact information on Rickettsia felis

Rickettsia felis infection acquired in Europe and documented by polymerase chain reaction [2].
We report the isolation and establishment of Rickettsia felis in the C6/36 cell line [3].
Amplification and sequencing of portions of the htrA and ompA genes in pooled samples (2 of 59) taken from fleas identified the pathogen Rickettsia felis [4].
On the basis of the results of citrate synthase gene sequence comparisons, as well as previous comparisons with 16S rRNA and 17-kDa-protein gene segments, we found that ELB is sufficiently genetically distinct from other rickettsiae to be designated a new species, Rickettsia felis [5].
Like Rickettsia felis, Orientia has many transposases and ankyrin and tetratricopeptide repeat domains [6].

Biological context of Rickettsia felis

Genome analysis of Rickettsia felis highlighted the presence of three patatin-like protein (PLP) genes (pat1, pat2A, and pat2B), whereas only one PLP gene (pat1) is found in the other sequenced rickettsial genomes [7].

Anatomical context of Rickettsia felis

Isolation of Rickettsia felis in the mosquito cell line C6/36 [3].

References

Phylogenetic analysis of the rompB genes of Rickettsia felis and Rickettsia prowazekii European-human and North American flying-squirrel strains. Moron, C.G., Bouyer, D.H., Yu, X.J., Foil, L.D., Crocquet-Valdes, P., Walker, D.H. Am. J. Trop. Med. Hyg. (2000) [Pubmed]
Rickettsia felis infection acquired in Europe and documented by polymerase chain reaction. Richter, J., Fournier, P.E., Petridou, J., Häussinger, D., Raoult, D. Emerging Infect. Dis. (2002) [Pubmed]
Isolation of Rickettsia felis in the mosquito cell line C6/36. Horta, M.C., Labruna, M.B., Durigon, E.L., Schumaker, T.T. Appl. Environ. Microbiol. (2006) [Pubmed]
Characterization of spotted fever group rickettsiae in flea and tick specimens from northern Peru. Blair, P.J., Jiang, J., Schoeler, G.B., Moron, C., Anaya, E., Cespedes, M., Cruz, C., Felices, V., Guevara, C., Mendoza, L., Villaseca, P., Sumner, J.W., Richards, A.L., Olson, J.G. J. Clin. Microbiol. (2004) [Pubmed]
Rickettsia felis: a new species of pathogenic rickettsia isolated from cat fleas. Higgins, J.A., Radulovic, S., Schriefer, M.E., Azad, A.F. J. Clin. Microbiol. (1996) [Pubmed]
New Perspectives on Rickettsial Evolution from New Genome Sequences of Rickettsia, particularly R. canadensis, and Orientia tsutsugamushi. Eremeeva, M.E., Madan, A., Shaw, C.D., Tang, K., Dasch, G.A. Ann. N. Y. Acad. Sci. (2005) [Pubmed]
Phylogenic Analysis of Rickettsial Patatin-like Protein with Conserved Phospholipase A2 Active Sites. Blanc, G., Renesto, P., Raoult, D. Ann. N. Y. Acad. Sci. (2005) [Pubmed]

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