The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Rickettsia prowazekii

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Rickettsia prowazekii


High impact information on Rickettsia prowazekii


Chemical compound and disease context of Rickettsia prowazekii


Biological context of Rickettsia prowazekii


Anatomical context of Rickettsia prowazekii


Gene context of Rickettsia prowazekii

  • Macrophage-like RAW264.7 cells are killed by the combination of gamma interferon (IFN-gamma) treatment and infection with Rickettsia prowazekii [24].
  • Role of the nitric oxide synthase pathway in inhibition of growth of interferon-sensitive and interferon-resistant Rickettsia prowazekii strains in L929 cells treated with tumor necrosis factor alpha and gamma interferon [25].
  • Modified Rickettsia prowazekii strains have been derived from the avirulent Madrid E strain by passage in the lungs of white mice (strain EVir) or by selection for resistance to gamma interferon (IFN-gamma) (strains 427-19 and 87-17) or alpha/beta interferon (IFN-alpha/beta) (strains 83-2P, 60P, 103-2P, and 110-1P) [10].
  • The gene (dnaG) coding for DNA primase in the obligate intracellular parasitic bacterium, Rickettsia prowazekii, has been isolated and characterized [26].
  • The transcripts of the citrate synthase-encoding gene (gltA) in Rickettsia prowazekii (Rp), an obligate intracellular parasitic bacterium, were analyzed by RNase protection (RP), primer extension (PE) and in vitro transcription assays [27].

Analytical, diagnostic and therapeutic context of Rickettsia prowazekii


  1. Jail fever (epidemic typhus) outbreak in Burundi. Raoult, D., Roux, V., Ndihokubwayo, J.B., Bise, G., Baudon, D., Marte, G., Birtles, R. Emerging Infect. Dis. (1997) [Pubmed]
  2. Susceptibility of Rickettsia tsutsugamushi Gilliam to gamma interferon in cultured mouse cells. Hanson, B. Infect. Immun. (1991) [Pubmed]
  3. Epidemic typhus meningitis in the southwestern United States. Massung, R.F., Davis, L.E., Slater, K., McKechnie, D.B., Puerzer, M. Clin. Infect. Dis. (2001) [Pubmed]
  4. Nucleotide sequence of the Rickettsia prowazekii citrate synthase gene. Wood, D.O., Williamson, L.R., Winkler, H.H., Krause, D.C. J. Bacteriol. (1987) [Pubmed]
  5. Phylogenetic analysis of the rompB genes of Rickettsia felis and Rickettsia prowazekii European-human and North American flying-squirrel strains. Moron, C.G., Bouyer, D.H., Yu, X.J., Foil, L.D., Crocquet-Valdes, P., Walker, D.H. Am. J. Trop. Med. Hyg. (2000) [Pubmed]
  6. Cloned mouse interferon-gamma inhibits the growth of Rickettsia prowazekii in cultured mouse fibroblasts. Turco, J., Winkler, H.H. J. Exp. Med. (1983) [Pubmed]
  7. Non-mitochondrial ATP transport. Winkler, H.H., Neuhaus, H.E. Trends Biochem. Sci. (1999) [Pubmed]
  8. Membrane topology of the Rickettsia prowazekii ATP/ADP translocase revealed by novel dual pho-lac reporters. Alexeyev, M.F., Winkler, H.H. J. Mol. Biol. (1999) [Pubmed]
  9. Cysteine-scanning mutagenesis and thiol modification of the Rickettsia prowazekii ATP/ADP translocase: characterization of TMs IV-VII and IX-XII and their accessibility to the aqueous translocation pathway. Audia, J.P., Roberts, R.A., Winkler, H.H. Biochemistry (2006) [Pubmed]
  10. Cytokine sensitivity and methylation of lysine in Rickettsia prowazekii EVir and interferon-resistant R. prowazekii strains. Turco, J., Winkler, H.H. Infect. Immun. (1994) [Pubmed]
  11. Some characteristics of heavy and light bands of Rickettsia prowazekii on Renografin gradients. Hanson, B.A., Wisseman, C.L., Waddell, A., Silverman, D.J. Infect. Immun. (1981) [Pubmed]
  12. Radioiodination of an outer membrane protein in intact Rickettsia prowazekii. Smith, D.K., Winkler, H.H. Infect. Immun. (1980) [Pubmed]
  13. Protein and RNA synthesis by isolated Rickettsia prowazekii. Winkler, H.H. Infect. Immun. (1987) [Pubmed]
  14. Cysteine-scanning mutagenesis and thiol modification of the Rickettsia prowazekii ATP/ADP translocase: evidence that TM VIII faces an aqueous channel. Winkler, H.H., Daugherty, R.M., Audia, J.P. Biochemistry (2003) [Pubmed]
  15. Roles of the Fc receptor and respiratory burst in killing of Rickettsia prowazekii by macrophagelike cell lines. Keysary, A., McCaul, T.F., Winkler, H.H. Infect. Immun. (1989) [Pubmed]
  16. Genomic organization of the Klebsiella pneumoniae cps region responsible for serotype K2 capsular polysaccharide synthesis in the virulent strain Chedid. Arakawa, Y., Wacharotayankun, R., Nagatsuka, T., Ito, H., Kato, N., Ohta, M. J. Bacteriol. (1995) [Pubmed]
  17. Deamination of deoxycytidine nucleotides by the obligate intracytoplasmic bacterium Rickettsia prowazekii. Speed, R.R., Winkler, H.H. J. Bacteriol. (1991) [Pubmed]
  18. Gene sequence-based criteria for identification of new rickettsia isolates and description of Rickettsia heilongjiangensis sp. nov. Fournier, P.E., Dumler, J.S., Greub, G., Zhang, J., Wu, Y., Raoult, D. J. Clin. Microbiol. (2003) [Pubmed]
  19. Rickettsia prowazekii and ATP/ADP translocase. Analysis of gene fusions encoding beta-galactosidase-ATP/ADP translocase fusion proteins. Plano, G.V., Wood, D.O., Winkler, H.H. Ann. N. Y. Acad. Sci. (1990) [Pubmed]
  20. Rickettsia prowazekii requires host cell serine and glycine for growth. Austin, F.E., Turco, J., Winkler, H.H. Infect. Immun. (1987) [Pubmed]
  21. Ultrastructure of Rickettsia rickettsii actin tails and localization of cytoskeletal proteins. Van Kirk, L.S., Hayes, S.F., Heinzen, R.A. Infect. Immun. (2000) [Pubmed]
  22. Detection of Rickettsia prowazekii in body lice and their feces by using monoclonal antibodies. Fang, R., Houhamdi, L., Raoult, D. J. Clin. Microbiol. (2002) [Pubmed]
  23. The use of DNase for preparation of host tissue DNA-free rickettsial suspensions. Ogarkova, O.A., Balayeva, N.M. Acta Virol. (1984) [Pubmed]
  24. Relationship of tumor necrosis factor alpha, the nitric oxide synthase pathway, and lipopolysaccharide to the killing of gamma interferon-treated macrophage-like RAW264.7 cells by Rickettsia prowazekii. Turco, J., Winkler, H.H. Infect. Immun. (1994) [Pubmed]
  25. Role of the nitric oxide synthase pathway in inhibition of growth of interferon-sensitive and interferon-resistant Rickettsia prowazekii strains in L929 cells treated with tumor necrosis factor alpha and gamma interferon. Turco, J., Winkler, H.H. Infect. Immun. (1993) [Pubmed]
  26. Characterization of the gene coding for the Rickettsia prowazekii DNA primase analogue. Marks, G.L., Wood, D.O. Gene (1993) [Pubmed]
  27. The citrate synthase-encoding gene of Rickettsia prowazekii is controlled by two promoters. Cai, J., Pang, H., Wood, D.O., Winkler, H.H. Gene (1995) [Pubmed]
  28. Characterization of the Madrid E strain of Rickettsia prowazekii purified by renografin density gradient centrifugation. Dasch, G.A., Weiss, E. Infect. Immun. (1977) [Pubmed]
  29. Differential requirements for enriched atmospheric carbon dioxide content for intracellular growth in cell culture among selected members of the genus Rickettsia. Kopmans-Gargantiel, A.I., Wisseman, C.L. Infect. Immun. (1981) [Pubmed]
  30. Sequence analysis of the Rickettsia prowazekii gyrA gene. Wood, D.O., Waite, R.T. Gene (1994) [Pubmed]
  31. Studies of Rickettsia prowazekii antigens in immunoblotting with specific sera of infected white mice. Eremeeva, M.E., Ignatovich, V.F., Nedvetzkaya, I.A., Balayeva, N.M. Mol. Gen. Mikrobiol. Virusol. (1994) [Pubmed]
WikiGenes - Universities