High impact information on Clematis

• Isolation and structures of two divinyl ether fatty acids from Clematis vitalba [1].
• The last compound was a new divinyl ether FA, and an analogous compound, i.e., 9-[1'(E),3'(Z)-nonadienyloxy]-8(Z)-nonenoic acid [8(Z)-colneleic acid], was obtained following incubation of linoleic acid with the Clematis homogenate [1].
• Bioassay-guided fractionation of the ethanol extract of the aerial parts of Clematis tangutica led to the isolation of two new antifungal triterpene saponins [2].
• Triterpenoid saponins from Clematis tangutica [3].
• Two new triterpenoid saponins, tanguticoside A and B along with seven known saponins vitalboside B, alpha-hederin, saponin PK, beta-hederin, saponin PJ3, saponin PE, and ciwujianoside A were isolated from aerial part of Clematis tangutica [3].

Associations of Clematis with chemical compounds

• An oleanolic acid based bisglycoside from Clematis montana roots [4].
• Clemontanoside-C, a new hederagenin-based saponin isolated from the stems of Clematis montana, was identified by chemical and spectroscopic methods as hederagenin-3-O-alpha-L-arabinopyranosyl (1-3)-alpha-L-rhamnopyranosyl (1-2)-alpha-L-arabinopyranoside [5].
• Clematoside-S, a triterpenoid saponin from the roots of Clematis grata [6].
• Sterol and lipid composition of Phymactis clematis (Drayton) [7].
• Anemonin, the dilactone of cyclobutane-1,2-diol-1,2-diacrylic acid derived from the cyclodimerization of protoanemonin, a known blistering agent, was isolated from Clematis hirsutissima, a plant used by the Nez Perce and Teton Sioux nations as a horse stimulant [8].

Gene context of Clematis

• The ethanol extracts of three Clematis species inhibited the activities of COX-1, COX-2 and 5-LOX in the different extents [9].
• We have previously reported that the ethanol extract of Clematis pickeringii inhibited COX-1 [9].
• The stem extract of Clematis pickeringii showed the highest inhibitory activities among the three species on COX-1, COX-2 and 5-LOX with the IC(50) values of 73.5, 101.2 and 29.3 microg/mL [9].
• Whereas staurosporin induced the degradation of 32 kDa caspase-3 precursor and the production of 85-kDa cleavage products of PARP in a time-dependent fashion, Clematis mandshurica treatment prevented those manifestations [10].
• Although the level of Bcl-2 expression was decreased after staurosporin treatment, it was sustained after the combination treatment with Clematis mandshurica [10].

References