Chemical Compound Review:
LINOLELAIDIC ACID octadeca-9,12-dienoic acid
Synonyms:
Leinoleic acid, AG-C-86061, AG-H-99435, AG-J-98407, KBioGR_000094, ...
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- Influence of diets containing eicosapentaenoic or docosahexaenoic acid on growth and metastasis of breast cancer cells in nude mice. Rose, D.P., Connolly, J.M., Rayburn, J., Coleman, M. J. Natl. Cancer Inst. (1995)
- Linoleic acid inhibition of naturally occurring lymphocytotoxicity to breast cancer-derived cells measured by a chromium-51 release assay. Samlaska, C.P. J. Natl. Cancer Inst. (1979)
- Prospective study of plasma fatty acids and risk of prostate cancer. Gann, P.H., Hennekens, C.H., Sacks, F.M., Grodstein, F., Giovannucci, E.L., Stampfer, M.J. J. Natl. Cancer Inst. (1994)
- Modulation of learning, pain thresholds, and thermoregulation in the rat by preparations of free purified alpha-linolenic and linoleic acids: determination of the optimal omega 3-to-omega 6 ratio. Yehuda, S., Carasso, R.L. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Abnormal polyunsaturated fatty acid patterns of serum lipids in alcoholism and cirrhosis: arachidonic acid deficiency in cirrhosis. Johnson, S.B., Gordon, E., McClain, C., Low, G., Holman, R.T. Proc. Natl. Acad. Sci. U.S.A. (1985)
- The effect of dietary fat on the rapid development of mammary tumors induced by 7,12-dimethylbenz(a)anthracene in SENCAR mice. Fischer, S.M., Conti, C.J., Locniskar, M., Belury, M.A., Maldve, R.E., Lee, M.L., Leyton, J., Slaga, T.J., Bechtel, D.H. Cancer Res. (1992)
- Dissociation of effects of dietary fatty acids on blood pressure and prostanoid metabolism in Goldblatt hypertensive rats. Codde, J.P., Beilin, L.J., Croft, K.D. J. Hypertens. (1984)
- Long-term effects of a linoleic acid-enriched diet, changes in body weight and alcohol consumption on serum total and HDL-cholesterol. Kromhout, D., Arntzenius, A.C., Kempen-Voogd, N., Kempen, H.J., Barth, J.D., van der Voort, H.A., van der Velde, E.A. Atherosclerosis (1987)
- Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase. Huang, J.T., Welch, J.S., Ricote, M., Binder, C.J., Willson, T.M., Kelly, C., Witztum, J.L., Funk, C.D., Conrad, D., Glass, C.K. Nature (1999)
- Fish oil prevents insulin resistance induced by high-fat feeding in rats. Storlien, L.H., Kraegen, E.W., Chisholm, D.J., Ford, G.L., Bruce, D.G., Pascoe, W.S. Science (1987)
- Visual membranes: specificity of fatty acid precursors for the electrical response to illumination. Wheeler, T.G., Benolken, R.M., Anderson, R.E. Science (1975)
- Trans-fatty acids and sudden cardiac death. Lemaitre, R.N., King, I.B., Mozaffarian, D., Sootodehnia, N., Siscovick, D.S. Atherosclerosis. Supplements. (2006)
- Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma. Han, K.H., Chang, M.K., Boullier, A., Green, S.R., Li, A., Glass, C.K., Quehenberger, O. J. Clin. Invest. (2000)
- Effect of dietary fat on growth kinetics of transplantable mammary adenocarcinoma in BALB/c mice. Gabor, H., Hillyard, L.A., Abraham, S. J. Natl. Cancer Inst. (1985)
- trans isomers of oleic and linoleic acids in adipose tissue and sudden cardiac death. Roberts, T.L., Wood, D.A., Riemersma, R.A., Gallagher, P.J., Lampe, F.C. Lancet (1995)
- Growth of T-lymphoma cells in serum-free medium: lack of involvement of the cyclic AMP pathway in long-term cultures. Darfler, F.J., Murakami, H., Insel, P.A. Proc. Natl. Acad. Sci. U.S.A. (1980)
- Mechanism for the antitumor and anticachectic effects of n-3 fatty acids. Sauer, L.A., Dauchy, R.T., Blask, D.E. Cancer Res. (2000)
- Selective cytotoxicity of phospholipids and diacylglycerols to rat 3Y1 fibroblasts transformed by adenovirus type 12 or its E1A gene. Shimura, H., Ohtsu, M., Matsuzaki, A., Mitsudomi, T., Onodera, K., Kimura, G. Cancer Res. (1988)
- 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. Shureiqi, I., Chen, D., Lee, J.J., Yang, P., Newman, R.A., Brenner, D.E., Lotan, R., Fischer, S.M., Lippman, S.M. J. Natl. Cancer Inst. (2000)
- Linoleic acid and its metabolites, hydroperoxyoctadecadienoic acids, stimulate c-Fos, c-Jun, and c-Myc mRNA expression, mitogen-activated protein kinase activation, and growth in rat aortic smooth muscle cells. Rao, G.N., Alexander, R.W., Runge, M.S. J. Clin. Invest. (1995)
- Intestinal effects of the products of lipid digestion on gastric electrical activity in the cat. Possible involvement of vagal intestinal receptors sensitive to lipids. Melone, J., Mei, N. Gastroenterology (1991)
- The effects of intestinal infusion of long-chain fatty acids on food intake in humans. French, S.J., Conlon, C.A., Mutuma, S.T., Arnold, M., Read, N.W., Meijer, G., Francis, J. Gastroenterology (2000)
- Modulation of rat gastric mucosal prostaglandin E2 release by dietary linoleic acid: effects on gastric acid secretion and stress-induced mucosal damage. Schepp, W., Steffen, B., Ruoff, H.J., Schusdziarra, V., Classen, M. Gastroenterology (1988)
- Utilization of arachidonic and linoleic acids by cultured human endothelial cells. Spector, A.A., Kaduce, T.L., Hoak, J.C., Fry, G.L. J. Clin. Invest. (1981)
- Effects of long-chain, saturated fatty acids on membrane microviscosity and adrenocorticotropin responsiveness of human adrenocortical cells in vitro. Whitcomb, R.W., Linehan, W.M., Knazek, R.A. J. Clin. Invest. (1988)
- Fatty acid composition of erythrocytes and plasma triglyceride and cardiovascular risk in Asian diabetic patients. Peterson, D.B., Fisher, K., Carter, R.D., Mann, J. Lancet (1994)
- Adipose tissue and platelet fatty acids and coronary heart disease in Scottish men. Wood, D.A., Butler, S., Riemersma, R.A., Thomson, M., Oliver, M.F., Fulton, M., Birtwhistle, A., Elton, R. Lancet (1984)
- Linoleic and eicosapentaenoic acids in adipose tissue and platelets and risk of coronary heart disease. Wood, D.A., Riemersma, R.A., Butler, S., Thomson, M., Macintyre, C., Elton, R.A., Oliver, M.F. Lancet (1987)
- Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Kliewer, S.A., Forman, B.M., Blumberg, B., Ong, E.S., Borgmeyer, U., Mangelsdorf, D.J., Umesono, K., Evans, R.M. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development. Miyazaki, M., Dobrzyn, A., Elias, P.M., Ntambi, J.M. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Interleukin-1 enhances the ability of cultured human umbilical vein endothelial cells to oxidize linoleic acid. Camacho, M., Godessart, N., Antón, R., García, M., Vila, L. J. Biol. Chem. (1995)
- Palmitate-induced interleukin-6 expression in human coronary artery endothelial cells. Staiger, H., Staiger, K., Stefan, N., Wahl, H.G., Machicao, F., Kellerer, M., Häring, H.U. Diabetes (2004)
- Hydroperoxy fatty acid cycling mediated by mitochondrial uncoupling protein UCP2. Jaburek, M., Miyamoto, S., Di Mascio, P., Garlid, K.D., Jezek, P. J. Biol. Chem. (2004)
- Effect of dietary fat on human breast cancer growth and lung metastasis in nude mice. Rose, D.P., Connolly, J.M., Meschter, C.L. J. Natl. Cancer Inst. (1991)
- Letter: Stability of serum oleate and linoleate levels after oral administration of oleic acid. Belin, J., Smith, A.D., Thompson, R.H. Lancet (1975)