Disease relevance of Garcinia mangostana

• Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells [1].

High impact information on Garcinia mangostana

• These results suggest that Garm FatA1 is at least partially responsible for determining the high stearate composition of mangosteen seed oil and that FatA as well FatB thioesterases have evolved for specialized roles [2].
• Three distinct acyl-ACP thioesterases were cloned from mangosteen seed cDNA; two representative of the FatA class and one representative of the FatB class [2].
• Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen) [3].
• The crude preparation was obtained by simple recrystallization of an ethylacetate extract of mangosteen pericarps [4].
• These results suggest that the 40% ethanol extract of mangosteen has potent inhibitory activities of both histamine release and prostaglandin E2 synthesis [5].

Associations of Garcinia mangostana with chemical compounds

• Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant [5].
• Polysaccharides from the pericarbs of mangosteen, Garcinia mangostana Linn., was obtained by treating the dried ground pericarbs with hot water followed by ethanol precipitation (M fraction) [6].
• Immunopharmacological activity of polysaccharide from the pericarb of mangosteen garcinia: phagocytic intracellular killing activities [6].

References