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Mice, Biozzi

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High impact information on Mice, Biozzi

  • Monoclonal antibodies directed against human renin were obtained by the fusing of myeloma cells with spleen cells from Balb/c or high-responder Biozzi mice injected with pure tumoral or highly purified renal renin [1].
  • An extensive search for in vivo immunomodulatory genes (Im genes) was made, using highly polymorphic DNA markers (microsatellites), in F2 hybrids between the two lines of mice selected for high (H) or low (L) Ab production (Biozzi mice) [2].
  • Allergen-specific immunogenicity of the mimotopes was proved in Biozzi mice [3].
  • Interactions between H-2 and background genes modulate collagen induced arthritis in high (HI) and low (LI) antibody producer Biozzi mice [4].
  • Tcrb and Tcrg gene polymorphism was investigated in high (H) and low (L) responder Biozzi mice from selection I, II, and GS by Southern blot analysis with appropriate V and C probes [5].

Gene context of Mice, Biozzi

  • Analysis of resistance data of backcrosses of (high x low)F1 with either parental strain showed this genetic control to be at least one other gene in the Biozzi mice, not linked to Ity [6].


  1. New monoclonal antibodies directed against human renin. Powerful tools for the investigation of the renin system. Galen, F.X., Devaux, C., Atlas, S., Guyenne, T., Menard, J., Corvol, P., Simon, D., Cazaubon, C., Richer, P., Badouaille, G. J. Clin. Invest. (1984) [Pubmed]
  2. Mapping of genes controlling quantitative antibody production in Biozzi mice. Puel, A., Groot, P.C., Lathrop, M.G., Demant, P., Mouton, D. J. Immunol. (1995) [Pubmed]
  3. Mapping of conformational IgE epitopes on Phl p 5a by using mimotopes from a phage display library. Hantusch, B., Krieger, S., Untersmayr, E., Schöll, I., Knittelfelder, R., Flicker, S., Spitzauer, S., Valenta, R., Boltz-Nitulescu, G., Scheiner, O., Jensen-Jarolim, E. J. Allergy Clin. Immunol. (2004) [Pubmed]
  4. Interactions between H-2 and background genes modulate collagen induced arthritis in high (HI) and low (LI) antibody producer Biozzi mice. Couderc, J., Gille Perramant, M.F., Bouthillier, Y., Mevel, J.C. Immunol. Lett. (1997) [Pubmed]
  5. Polymorphism of Tcrb and Tcrg genes in Biozzi mice: segregation analysis of a new Tcrg haplotype with antibody responsiveness. Vidard, L., Roger, T., Pham, G., Couderc, J., Bouthillier, Y., Mevel, J.C., Mouton, D., Seman, M. Immunogenetics (1990) [Pubmed]
  6. Genetic control of resistance to Salmonella typhimurium infection in high and low antibody responder mice. Plant, J.E., Glynn, A.A. Clin. Exp. Immunol. (1982) [Pubmed]
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