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Gene Review

Tcrg  -  T cell receptor gamma chain

Mus musculus

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Disease relevance of Tcrg


High impact information on Tcrg


Biological context of Tcrg


Anatomical context of Tcrg

  • We conclude that the spleen is one of the extrathymic sites where T-cell progenitors can rearranged Tcrd and Tcrg genes [13].
  • We have isolated an unusual T cell receptor gamma chain cDNA clone (gamma 7.1) from a library made from RNA derived from adult thymus of C57BL/Ka mice [14].

Other interactions of Tcrg


  1. Relationship of the genes for Chediak-Higashi syndrome (beige) and the T-cell receptor gamma chain in mouse and man. Holcombe, R.F., Strauss, W., Owen, F.L., Boxer, L.A., Warren, R.W., Conley, M.E., Ferrara, J., Leavitt, R.Y., Fauci, A.S., Taylor, B.A. Genomics (1987) [Pubmed]
  2. Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers. Wang, S.W., Speck, N.A. Mol. Cell. Biol. (1992) [Pubmed]
  3. A novel TARP-promoter-based adenovirus against hormone-dependent and hormone-refractory prostate cancer. Cheng, W.S., Kraaij, R., Nilsson, B., van der Weel, L., de Ridder, C.M., Tötterman, T.H., Essand, M. Mol. Ther. (2004) [Pubmed]
  4. Defective V-to-J recombination of T cell receptor gamma chain genes in scid mice. Schuler, W., Schuler, A., Bosma, M.J. Eur. J. Immunol. (1990) [Pubmed]
  5. Lineage switch in childhood leukemia with monosomy 7 and reverse of lineage switch in severe combined immunodeficient mice. Fujisaki, H., Hara, J., Takai, K., Nakanishi, K., Matsuda, Y., Ohta, H., Osugi, Y., Tokimasa, S., Taniike, M., Hosoi, G., Sako, M., Okada, S. Exp. Hematol. (1999) [Pubmed]
  6. Expression of the T-cell receptor gamma-chain gene products on the surface of peripheral T cells and T-cell blasts generated by allogeneic mixed lymphocyte reaction. Maeda, K., Nakanishi, N., Rogers, B.L., Haser, W.G., Shitara, K., Yoshida, H., Takagaki, Y., Augustin, A.A., Tonegawa, S. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  7. T-cell receptor genes in autoimmune mice: T-cell subsets have unexpected T-cell receptor gene programs. Hashimoto, Y., Yui, K., Littman, D., Greene, M.I. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  8. The murine gamma-chain of the T cell receptor is closely linked to a spermatocyte specific histone gene and the beige coat color locus on chromosome 13. Owen, F.L., Taylor, B.A., Zweidler, A., Seidman, J.G. J. Immunol. (1986) [Pubmed]
  9. Expansion of myelopoietic precursors and inhibition of B-cell precursors in mice that express a T-cell receptor gamma (V gamma 1.1J gamma 4C gamma 4) transgene. Ferrick, D.A., Cumano, A., Furlonger, C., Min, X., Iscove, N.N., Paige, C.J., Mak, T.W. J. Cell. Physiol. (1991) [Pubmed]
  10. Sequence and diversity of rabbit T-cell receptor gamma chain genes. Isono, T., Kim, C.J., Seto, A. Immunogenetics (1995) [Pubmed]
  11. Polymorphism of Tcrb and Tcrg genes in Biozzi mice: segregation analysis of a new Tcrg haplotype with antibody responsiveness. Vidard, L., Roger, T., Pham, G., Couderc, J., Bouthillier, Y., Mevel, J.C., Mouton, D., Seman, M. Immunogenetics (1990) [Pubmed]
  12. Promoter region of mouse Tcrg genes. Ishimi, Y., Huang, Y.Y., Ohta, S., Hamano, F., Nagai, K., Takagaki, Y. Immunogenetics (1996) [Pubmed]
  13. Rearrangement patterns of T-cell receptor genes in the spleen of athymic (nu/nu) young mice. Palacios, R., Samaridis, J. Immunogenetics (1991) [Pubmed]
  14. Diversity of the mouse T cell receptor C gamma 1 gene: structural analysis in C57BL/Ka. Rathbun, G.A., Born, W., Kuziel, W.A., Tucker, P.W. Immunogenetics (1988) [Pubmed]
  15. New T-cell receptor gamma haplotypes in wild mice and evidence for limited Tcrg-V gene polymorphism. Roger, T., Pépin, L.F., Jouvin-Marche, E., Cazenave, P.A., Seman, M. Immunogenetics (1993) [Pubmed]
  16. Cloning, genetic mapping, and expression analysis of a mouse renal sodium-dependent phosphate cotransporter. Chong, S.S., Kozak, C.A., Liu, L., Kristjansson, K., Dunn, S.T., Bourdeau, J.E., Hughes, M.R. Am. J. Physiol. (1995) [Pubmed]
  17. In vitro immune-receptor gene rearrangements in clonal thymic lymphomas induced by Abelson murine leukemia virus. Saggioro, D., D'Andrea, E., Chieco-Bianchi, L. Tumori. (1989) [Pubmed]
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