Disease relevance of Mammea

• Preliminary studies of Mammea americana L. (Guttiferae) bark/latex extract point to an effective antiulcer effect on gastric ulcer models in mice [1].

High impact information on Mammea

• Antioxidant-guided fractionation of Mammea americana L. seeds resulted in the identification of three new isoprenylated coumarins, mammea B/BA hydroxycyclo F (1), mammea E/BC (2), and mammea E/BD (3) [2].
• Antioxidant and cytotoxic isoprenylated coumarins from Mammea americana [2].
• Antifungal properties of surangin B, a coumarin from Mammea longifolia [3].
• The mixtures of mammea A/BA + A/BB, mammea B/BA + B/BB and mammea C/OA + C/OB were also highly active (IC50 < 4.05 microM) [4].
• Nagkesar (buds of Mammea longifolia) is extensively used in culinary preparations especially in spice blend in India. Previously thirteen compounds were identified from the medium polar fractions of methanol extract of buds of M. longifolia [5].

Associations of Mammea with chemical compounds

• Cytotoxic coumarins from Mammea harmandii [6].
• Acylated and non-acylated flavonol monoglycosides from the Indian minor spice Nagkesar (Mammea longifolia) [7].
• This is the first report to indicate that Mammea buds contain antioxidant and radical scavenging procyanidin oligomers [5].
• Occurrence of antioxidant and radical scavenging proanthocyanidins from the Indian minor spice nagkesar (Mammea longifolia planch and triana syn) [5].
• None of the xanthones or the flavonoids were sulfonated by SULT2A1, whereas the coumarin mammea A/BA was a substrate for this enzyme [8].

Analytical, diagnostic and therapeutic context of Mammea

• A methanol extract of nagkesar (buds of Mammea longifolia), which showed strong radical scavenging activity, yielded 13 compounds by separations using column chromatography and HPLC [7].

References