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MeSH Review:

Ampelopsis

Lee, H. et al., Murakami, T. et al., Hwang, Y.H. et al., Du, Q. et al., Yabe, N. et al., et al.

Wu, Yen, Wang, Weng, Du, Chen, Jerz, Winterhalter,

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High impact information on Ampelopsis

Recently, we found a strong inhibitor of AP-1 transcriptional activity, named momordin I, based on the structure of oleanolic acid glycosides and originally isolated from Ampelopsis radix [1].
Preparative separation of flavonoid glycosides in leaves extract of Ampelopsis grossedentata using high-speed counter-current chromatography [2].
Among them, there were 5 kinds of crude drugs, Actinidia chinensis P., Artemisia lavendulaefolia DC., Prunella vulgaris L., Paris polyphylla S. and Ampelopsis brevipedunculata T., containing antimutagenic factors against both picrolonic acid- and benzo[a]pyrene-induced mutation [3].
Hepatoprotective activity of tocha, the stems and leaves of Ampelopsis grossedentata, and ampelopsin [4].
Hepatoprotective effect of the leaves and stems of Ampelopsis grossedentata together with its main constituent, ampelopsin, were examined on D-galactosamine induced liver injury in rats [4].

Associations of Ampelopsis with chemical compounds

The methanol extract of Ampelopsis radix reduced Jun/Foc retardation remarkably [5].
We characterized the effects of an ethanol-extract of the berries of Ampelopsis brevipedunculata (Maxim.) Trautv [6].

Gene context of Ampelopsis

Momordin I, a compound of ampelopsis radix, inhibits AP-1 activation induced by phorbol ester [7].
Antioxidant activity of Porcelainberry (Ampelopsis brevipedunculata (Maxim.) Trautv.) [8].

References

Momordin I, an inhibitor of AP-1, suppressed osteoclastogenesis through inhibition of NF-kappaB and AP-1 and also reduced osteoclast activity and survival. Hwang, Y.H., Lee, J.W., Hahm, E.R., Jung, K.C., Lee, J.H., Park, C.H., Rhee, H.S., Ryu, J.M., Kim, H.K., Yang, C.H. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
Preparative separation of flavonoid glycosides in leaves extract of Ampelopsis grossedentata using high-speed counter-current chromatography. Du, Q., Chen, P., Jerz, G., Winterhalter, P. Journal of chromatography. A. (2004) [Pubmed]
Antimutagenic activity of extracts from anticancer drugs in Chinese medicine. Lee, H., Lin, J.Y. Mutat. Res. (1988) [Pubmed]
Hepatoprotective activity of tocha, the stems and leaves of Ampelopsis grossedentata, and ampelopsin. Murakami, T., Miyakoshi, M., Araho, D., Mizutani, K., Kambara, T., Ikeda, T., Chou, W.H., Inukai, M., Takenaka, A., Igarashi, K. Biofactors (2004) [Pubmed]
Momordins inhibit both AP-1 function and cell proliferation. Lee, D.K., Kim, B., Lee, S.G., Gwon, H.J., Moon, E.Y., Hwang, H.S., Seong, S.K., Lee, M., Lim, M.J., Sung, H.J., Shin, D.H., Yoon, S.J., Yang, C.H. Anticancer Res. (1998) [Pubmed]
An ethanol-extract of Ampelopsis brevipedunculata (Vitaceae) berries decreases ferrous iron-stimulated hepatocyte injury in culture. Yabe, N., Tanaka, K., Matsui, H. Journal of ethnopharmacology. (1998) [Pubmed]
Momordin I, a compound of ampelopsis radix, inhibits AP-1 activation induced by phorbol ester. Park, S., Lee, D.K., Whang, Y.H., Yang, C.H. Cancer Lett. (2000) [Pubmed]
Antioxidant activity of Porcelainberry (Ampelopsis brevipedunculata (Maxim.) Trautv.). Wu, M.J., Yen, J.H., Wang, L., Weng, C.Y. Am. J. Chin. Med. (2004) [Pubmed]

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