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Chemical Compound Review

Eudesmane     (3R,4aS,5R,8aR)-5,8a- dimethyl-3-propan-2...

Synonyms: AG-J-68573, CHEBI:36522, KST-1A5760, AC1L4VZH, CTK4I9841, ...
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High impact information on Eudesmane


Biological context of Eudesmane


Anatomical context of Eudesmane

  • Yomogin (1), an eudesmane sesquiterpene isolated from Artemisia princeps, was tested for the effects on the degranulation process of cultured mast cells and on the nitric oxide production in LPS-activated murine macrophages [7].
  • Investigation of lipophilic exudates from the aerial parts of Balsamorhiza sagittata and B. macrophylla afforded three new highly oxygenated guaianolides (1-3), in addition to known guaianolides, germacranolide and eudesmane acids [8].

Associations of Eudesmane with other chemical compounds


Gene context of Eudesmane


  1. Stabilisation of eudesmane cation by tryptophan 334 during aristolochene synthase catalysis. Deligeorgopoulou, A., Taylor, S.E., Forcat, S., Allemann, R.K. Chem. Commun. (Camb.) (2003) [Pubmed]
  2. Novel approach for the stereocontrolled construction of eudesmane skeleton: a concise synthesis of (+/-)-balanitol. Zhang, Z., Li, W.D., Li, Y. Org. Lett. (2001) [Pubmed]
  3. Regioselective enzymatic acylations of polyhydroxylated eudesmanes: semisynthesis, theoretical calculations, and biotransformation of cyclic sulfites. García-Granados, A., Melguizo, E., Parra, A., Simeó, Y., Viseras, B., Dobado, J.A., Molina, J., Arias, J.M. J. Org. Chem. (2000) [Pubmed]
  4. Synergistic induction of 1,25-dihydroxyvitamin D(3)- and all-trans-retinoic acid-induced differentiation of HL-60 leukemia cells by yomogin, a sesquiterpene lactone from Artemisia princeps. Kim, S.H., Kim, T.S. Planta Med. (2002) [Pubmed]
  5. Biotransformation of alpha- and 6beta-santonin by fungus and plant cell cultures. Yang, L., Dai, J., Sakai, J.I., Ando, M. Journal of Asian natural products research. (2006) [Pubmed]
  6. Improved microbiological hydroxylation of sesquiterpenoids: semisynthesis, structural determination and biotransformation studies of cyclic sulfite eudesmane derivatives. García-Granados, A., Gutiérrez, M.C., Rivas, F. Org. Biomol. Chem. (2003) [Pubmed]
  7. Yomogin inhibits the degranulation of mast cells and the production of the nitric oxide in activated RAW 264.7 cells. Ryu, S.Y., Oak, M.H., Kim, K.M. Planta Med. (2000) [Pubmed]
  8. Highly oxygenated guaianolides and eudesman-12-oic acids from Balsamorhiza sagittata and Balsamorhiza macrophylla. El-Hamd H Mohamed, A., Ahmed, A.A., Wollenweber, E., Bohm, B., Asakawa, Y. Chem. Pharm. Bull. (2006) [Pubmed]
  9. Eudesmanolides and Other Constituents from Artemisia argyi. Tan, R., Jia, Z. Planta Med. (1992) [Pubmed]
  10. New Eudesmane Sesquiterpene and Other Constituents from Artemisia mongolica. Hu, J., Zhu, Q., Bai, S., Jia, Z. Planta Med. (1996) [Pubmed]
  11. Structures of new friedelane- and norfriedelane-type triterpenes and polyacylated eudesmane-type sesquiterpene from Salacia chinensis LINN. (S. prinoides DC., Hippocrateaceae) and radical scavenging activities of principal constituents. Kishi, A., Morikawa, T., Matsuda, H., Yoshikawa, M. Chem. Pharm. Bull. (2003) [Pubmed]
  12. A New Eudesmane Derivative and a New Fatty Acid Ester from Sambucus williamsii. Yang, X., Wong, M., Wang, N., Chan, A.S., Yao, X. Chem. Pharm. Bull. (2006) [Pubmed]
  13. Sesquiterpenes from Ferula penninervis. Shikishima, Y., Takaishi, Y., Honda, G., Ito, M., Takeda, Y., Tori, M., Takaoka, S., Kodzhimatov, O.K., Ashurmetov, O. J. Nat. Prod. (2002) [Pubmed]
  14. Medicinal flowers. I. Aldose reductase inhibitors and three new eudesmane-type sesquiterpenes, kikkanols A, B, and C, from the flowers of Chrysanthemum indicum L. Yoshikawa, M., Morikawa, T., Murakami, T., Toguchida, I., Harima, S., Matsuda, H. Chem. Pharm. Bull. (1999) [Pubmed]
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