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Chemical Compound Review:

Friedelane 4,4a,6a,6b,8a,11,11,14a- octamethyl-1,2,3,4...

Synonyms: AC1LCOPC, AGN-PC-00PO4U, D:A-Friedooleanane

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High impact information on Friedelane

Molecular structures and antiviral activities of naturally occurring and modified cassane furanoditerpenoids and friedelane triterpenoids from Caesalpinia minax [1].
Synthetic secofriedelane and friedelane derivatives as inhibitors of human lymphocyte proliferation and growth of human cancer cell lines in vitro [2].
Antidiabetic principles of natural medicines. IV. Aldose reductase and qlpha-glucosidase inhibitors from the roots of Salacia oblonga Wall. (Celastraceae): structure of a new friedelane-type triterpene, kotalagenin 16-acetate [3].
A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa [4].
Three new friedelane-type triterpenoids, 3,4-secofriedelan-3,28-dioic acid (1), 27-hydroxyacetate canophyllic acid (2) and 3-oxo-27-hydroxyacetate friedelan-28-oic acid (3), were isolated from the leaves of Calophyllum inophyllum (Clusiaceae) grown in French Polynesia [5].

Analytical, diagnostic and therapeutic context of Friedelane

These results suggest the possibility of further biotechnological exploration of sedative friedelane biosynthesis by in vitro plant organ cultures [6].

References

Molecular structures and antiviral activities of naturally occurring and modified cassane furanoditerpenoids and friedelane triterpenoids from Caesalpinia minax. Jiang, R.W., Ma, S.C., He, Z.D., Huang, X.S., But, P.P., Wang, H., Chan, S.P., Ooi, V.E., Xu, H.X., Mak, T.C. Bioorg. Med. Chem. (2002) [Pubmed]
Synthetic secofriedelane and friedelane derivatives as inhibitors of human lymphocyte proliferation and growth of human cancer cell lines in vitro. Moiteiro, C., Justino, F., Tavares, R., Marcelo-Curto, M.J., Florêncio, M.H., Nascimento, M.S., Pedro, M., Cerqueira, F., Pinto, M.M. J. Nat. Prod. (2001) [Pubmed]
Antidiabetic principles of natural medicines. IV. Aldose reductase and qlpha-glucosidase inhibitors from the roots of Salacia oblonga Wall. (Celastraceae): structure of a new friedelane-type triterpene, kotalagenin 16-acetate. Matsuda, H., Murakami, T., Yashiro, K., Yamahara, J., Yoshikawa, M. Chem. Pharm. Bull. (1999) [Pubmed]
Friedelane triterpenoids from Maytenus macrocarpa. Chávez, H., Estévez-Braun, A., Ravelo, A.G., González, A.G. J. Nat. Prod. (1998) [Pubmed]
Structures of new secofriedelane and friedelane acids from Calophyllum inophyllum of French Polynesia. Laure, F., Herbette, G., Faure, R., Bianchini, J.P., Raharivelomanana, P., Fogliani, B. Magnetic resonance in chemistry : MRC. (2005) [Pubmed]
Genetic transformation of Glaphimia glauca by Agrobacterium rhizogenes and the production of norfriedelanes. Náder, B.L., Cardoso Taketa, A.T., Iturriaga, G., Pereda-Miranda, R., Villarreal, M.L. Planta Med. (2004) [Pubmed]

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