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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Hand Bones

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Disease relevance of Hand Bones


High impact information on Hand Bones

  • Between subjects, shortening ranged from -2 to -10.4 SDS and involved 1-19 hand bones (5.3-100%) [3].
  • The metacarpophalangeal pattern profile (MCPP), a radiological method in which the 19 tubular hand bones are assessed, has been used in the diagnosis of various syndromes [4].
  • The results of bivariate variance decomposition analysis showed no significant genetic and phenotypic correlation between the mineral density of hand bones and IGFBP-3 [5].
  • The feasibility of expressing periosteal resorption (PR) in hand bones quantitatively as a measure of skeletal involvement of hyperparathyroidism, was tested by measuring the length of surface irregularities in medial and lateral surfaces of the middle phlanges of digits II--IV in one hand [6].
  • From hand radiographs, the measurement of the bone density of hand bones is automatically performed, using units relative to an aluminium wedge, in order to know the absorption of the ray light intensity respect to a known substance [7].

Gene context of Hand Bones


  1. Effect of protein energy malnutrition and vitamin A deficiency on the bones of hand and wrist. Vijayaraghavan, R., Pandiarajan, V., Subramanian, A., Viswanathan, J. Indian pediatrics. (1982) [Pubmed]
  2. Radiographic hand abnormalities in fifteen cases of Crouzon syndrome. Kaler, S.G., Bixler, D., Yu, P.L. J. Craniofac. Genet. Dev. Biol. (1982) [Pubmed]
  3. Brachydactyly in 14 genetically characterized pseudohypoparathyroidism type Ia patients. de Sanctis, L., Vai, S., Andreo, M.R., Romagnolo, D., Silvestro, L., de Sanctis, C. J. Clin. Endocrinol. Metab. (2004) [Pubmed]
  4. Metacarpophalangeal pattern profile in Marfan syndrome and Marfan-like patients. de Oliveira Sobrinho, R.P., Moretti-Ferreira, D., Contini, A., Norato, D.Y. Am. J. Med. Genet. (1997) [Pubmed]
  5. Pedigree-based quantitative genetic analysis of interindividual variation in circulating levels of IGFBP-3. Pantsulaia, I.a., Pantsulaia, I., Trofimov, S., Kobyliansky, E., Livshits, G. J. Bone Miner. Metab. (2002) [Pubmed]
  6. Microradioscopic quantitation of periosteal resorption in secondary hyperparathyroidism of chronic renal failure. Meema, H.E., Meema, S. Clin. Orthop. Relat. Res. (1978) [Pubmed]
  7. Hand bone segmentation in radioabsorptiometry images for computerised bone mass assessment. Sotoca, J.M., Iñesta, J.M., Belmonte, M.A. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. (2003) [Pubmed]
  8. Prospective X-ray densitometry and ultrasonography study of the hand bones of patients with rheumatoid arthritis of recent onset. Daragon, A., Krzanowska, K., Vittecoq, O., Ménard, J.F., Hau, I., Jouen-Beades, F., Lesage, C., Bertho, J.M., Tron, F., Le Loët, X. Joint, bone, spine : revue du rhumatisme. (2001) [Pubmed]
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