Disease relevance of Differential Threshold

• Monaural and binaural intensity difference limens for 75-dB SPL pure tones were determined for 6 normal subjects and for 6 subjects with cochlear hearing loss [1].

Psychiatry related information on Differential Threshold

• Additional special tests included the precedence effect in sound localization, measurement of frequency difference limens for short (5 msec) and long (200 msec) duration tones, and the P300 event-related potential [2].
• Psychometric functions and the associated indices of discriminative performance (i.e., the point of subjective equality [PSE], just noticeable difference, and Weber fraction) were obtained with the method of constant stimuli using perceptual and remembered line-length standards [3].

High impact information on Differential Threshold

• The performance decrement in the blue cone monochromats was probably not associated with rod saturation, as the field action spectrum to cause a just-noticeable-difference (jnd) decrement in discrimination was poorly fitted by a rhodopsin action spectrum [4].
• As pimozide did not affect either the threshold for sweetness perception or the discrimination of a just noticeable difference, the decreased responsiveness of neuroleptic-treated rats to sweet rewards cannot be explained by a change in the perception of sweetness [5].
• Nicotinic acetylcholine and D1-like receptor blockade in the CeA or the dlBNST did not induce differential threshold elevations in nicotine- and saline-treated rats [6].
• Finally, in experiment 4, differential threshold functions were constructed with either NHDC or sucrose added [7].
• In this study, the existence of statistical relationships between intensity difference limens (IDLs) and MOCS functioning was tested in humans [8].

Chemical compound and disease context of Differential Threshold

• Effect of acetazolamide on the differential threshold [9].
• Following the oral administration of three 250-mg doses of acetazolamide sodium to nine patients with glaucomatous visual-field defects, a statistically significant improvement in the differential threshold was observed, whereas in 16 glaucoma suspects, no change could be detected [9].
• A generalized Weber model provided a better approximation to the growth in the difference limen as a function of signal than a generalized Counter model [10].
• The intersubject variability of the difference limens for frequency (delta F) was large, as reported by other investigators, but similar in magnitude to the variability of the difference limens for intensity (delta I) from three of the same subjects in an intensity discrimination experiment [11].

Gene context of Differential Threshold

• A two interval forced choice constant stimuli method was used to determine: (i) the point of subjective equality (PSE); and (ii) the just-noticeable-difference (JND) in contrast for two luminance gratings, one held in short-term visual memory [12].
• For normally hearing subjects tested at a level of 70 dB SPL per component, thresholds for detecting the phase shift [i.e., phase difference limens (DLs)] were smallest (2 degrees-4 degrees) for harmonics above the eighth and for the lowest fundamental frequency (F0) [13].
• Loudness functions and frequency difference limens (DLFs) were measured in five subjects with steeply sloping high-frequency sensorineural hearing loss [14].
• The dynamic range of current, the pitch variation with repetition rate, and the difference limens for repetition rate were found to be similar to MPP and SPP [15].
• The Novel technique gave the most accurate measurement of QT interval, T3 (a differential threshold method) was the next most accurate by a large margin [16].

References