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MeSH Review

Differential Threshold

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Disease relevance of Differential Threshold


Psychiatry related information on Differential Threshold

  • Additional special tests included the precedence effect in sound localization, measurement of frequency difference limens for short (5 msec) and long (200 msec) duration tones, and the P300 event-related potential [2].
  • Psychometric functions and the associated indices of discriminative performance (i.e., the point of subjective equality [PSE], just noticeable difference, and Weber fraction) were obtained with the method of constant stimuli using perceptual and remembered line-length standards [3].

High impact information on Differential Threshold

  • The performance decrement in the blue cone monochromats was probably not associated with rod saturation, as the field action spectrum to cause a just-noticeable-difference (jnd) decrement in discrimination was poorly fitted by a rhodopsin action spectrum [4].
  • As pimozide did not affect either the threshold for sweetness perception or the discrimination of a just noticeable difference, the decreased responsiveness of neuroleptic-treated rats to sweet rewards cannot be explained by a change in the perception of sweetness [5].
  • Nicotinic acetylcholine and D1-like receptor blockade in the CeA or the dlBNST did not induce differential threshold elevations in nicotine- and saline-treated rats [6].
  • Finally, in experiment 4, differential threshold functions were constructed with either NHDC or sucrose added [7].
  • In this study, the existence of statistical relationships between intensity difference limens (IDLs) and MOCS functioning was tested in humans [8].

Chemical compound and disease context of Differential Threshold


Gene context of Differential Threshold

  • A two interval forced choice constant stimuli method was used to determine: (i) the point of subjective equality (PSE); and (ii) the just-noticeable-difference (JND) in contrast for two luminance gratings, one held in short-term visual memory [12].
  • For normally hearing subjects tested at a level of 70 dB SPL per component, thresholds for detecting the phase shift [i.e., phase difference limens (DLs)] were smallest (2 degrees-4 degrees) for harmonics above the eighth and for the lowest fundamental frequency (F0) [13].
  • Loudness functions and frequency difference limens (DLFs) were measured in five subjects with steeply sloping high-frequency sensorineural hearing loss [14].
  • The dynamic range of current, the pitch variation with repetition rate, and the difference limens for repetition rate were found to be similar to MPP and SPP [15].
  • The Novel technique gave the most accurate measurement of QT interval, T3 (a differential threshold method) was the next most accurate by a large margin [16].


  1. Monaural and binaural intensity discrimination in normal and cochlear-impaired listeners. Hall, J.W., Fernandes, M.A. Audiology (1983) [Pubmed]
  2. Central auditory processing in an adult with congenital absence of left temporal lobe. Allen, R.L., Cranford, J.L., Pay, N. Journal of the American Academy of Audiology. (1996) [Pubmed]
  3. The discriminability of remembered magnitudes. Baranski, J.V., Petrusic, W.M. Memory & cognition. (1992) [Pubmed]
  4. Wavelength discrimination deteriorates with illumination in blue cone monochromats. Young, R.S., Price, J. Invest. Ophthalmol. Vis. Sci. (1985) [Pubmed]
  5. Pimozide does not impair sweetness discrimination. Willner, P., Papp, M., Phillips, G., Maleeh, M., Muscat, R. Psychopharmacology (Berl.) (1990) [Pubmed]
  6. Blockade of nicotinic acetylcholine or dopamine D1-like receptors in the central nucleus of the amygdala or the bed nucleus of the stria terminalis does not precipitate nicotine withdrawal in nicotine-dependent rats. Jonkman, S., Markou, A. Neurosci. Lett. (2006) [Pubmed]
  7. Neohesperidin dihydrochalcone is not a taste enhancer in aqueous sucrose solutions. Kroeze, J.H. Chem. Senses (2000) [Pubmed]
  8. Relationship between auditory intensity discrimination in noise and olivocochlear efferent system activity in humans. Micheyl, C., Perrot, X., Collet, L. Behav. Neurosci. (1997) [Pubmed]
  9. Effect of acetazolamide on the differential threshold. Flammer, J., Drance, S.M. Arch. Ophthalmol. (1983) [Pubmed]
  10. Duration discrimination by rats. Church, R.M., Getty, D.J., Lerner, N.D. Journal of experimental psychology. Animal behavior processes. (1976) [Pubmed]
  11. Frequency discrimination in the monkey. Prosen, C.A., Moody, D.B., Sommers, M.S., Stebbins, W.C. The Journal of the Acoustical Society of America. (1990) [Pubmed]
  12. Contrast transfer characteristics of visual short-term memory. Lee, B., Harris, J. Vision Res. (1996) [Pubmed]
  13. Difference limens for phase in normal and hearing-impaired subjects. Moore, B.C., Glasberg, B.R. The Journal of the Acoustical Society of America. (1989) [Pubmed]
  14. Loudness perception and frequency discrimination in subjects with steeply sloping hearing loss: possible correlates of neural plasticity. McDermott, H.J., Lech, M., Kornblum, M.S., Irvine, D.R. The Journal of the Acoustical Society of America. (1998) [Pubmed]
  15. Psychophysical studies evaluating the feasibility of a speech processing strategy for a multiple-channel cochlear implant. Tong, Y.C., Blamey, P.J., Dowell, R.C., Clark, G.M. The Journal of the Acoustical Society of America. (1983) [Pubmed]
  16. Accuracy of popular automatic QT interval algorithms assessed by a 'gold standard' and comparison with a Novel method: computer simulation study. Hunt, A.C. BMC cardiovascular disorders [electronic resource]. (2005) [Pubmed]
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