The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Sunburn


High impact information on Sunburn

  • Although the absolute risk of SCC associated with sunburns was similar across genotypes, the relative risk of SCC associated with painful sunburn history was significantly higher for homozygous variants than wild types (OR 6.8 for gln399gln and 1.5 for arg399arg) [3].
  • Risk of all types of CMM and SSM also increased with increasing number of sunburns for all age groups and with lack of use of sunscreen [4].
  • METHODS: Data from the 2000 National Health Interview Survey Cancer Control Module were used to calculate the number of sunburns (0, 1, 2, or > or = 3) experienced during the past year by age, sex, race/ethnicity, and skin sensitivity to sun exposure [5].
  • Ultraviolet recall or sunburn reactivation is an uncommon phenomenon that has been most frequently reported in patients who suffered sunburns and then subsequently underwent therapy with methotrexate [6].
  • RESULTS: There was no evidence for sun-related damage in the entire patient group, despite a significant number of positive cases with a history of sunburns in early childhood and continuous accumulation of epidermal H(2)O(2) [7].

Gene context of Sunburn

  • Univariate results from analysis of factors related to sun exposure showed that the risk of all histologic types of CMM, SSM, and NM increased with increasing tendency of the subject to sunburn and with history of increased severity and/or frequency of sunburns up to age 12 years [4].
  • For preventing excessive solar exposure which leads to sunburns, we recommend interventions like a Pilot Program for photoprotection education and Sun Awareness Week to improve knowledge and sun protection behavior [8].
  • RESULTS: Men had a higher risk as assessed by skin type, ultraviolet exposure, family history, number of moles and sunburns during childhood [9].


  1. At what age do sunburn episodes play a crucial role for the development of malignant melanoma. Westerdahl, J., Olsson, H., Ingvar, C. Eur. J. Cancer (1994) [Pubmed]
  2. The multicentre south European study 'Helios'. I: Skin characteristics and sunburns in basal cell and squamous cell carcinomas of the skin. Zanetti, R., Rosso, S., Martinez, C., Navarro, C., Schraub, S., Sancho-Garnier, H., Franceschi, S., Gafà, L., Perea, E., Tormo, M.J., Laurent, R., Schrameck, C., Cristofolini, M., Tumino, R., Wechsler, J. Br. J. Cancer (1996) [Pubmed]
  3. The XRCC1 Arg399Gln polymorphism, sunburn, and non-melanoma skin cancer: evidence of gene-environment interaction. Nelson, H.H., Kelsey, K.T., Mott, L.A., Karagas, M.R. Cancer Res. (2002) [Pubmed]
  4. Cutaneous melanoma in women. I. Exposure to sunlight, ability to tan, and other risk factors related to ultraviolet light. Holly, E.A., Aston, D.A., Cress, R.D., Ahn, D.K., Kristiansen, J.J. Am. J. Epidemiol. (1995) [Pubmed]
  5. Correlates of sunburn experiences among U.S. adults: results of the 2000 National Health Interview Survey. Hall, H.I., Saraiya, M., Thompson, T., Hartman, A., Glanz, K., Rimer, B. Public health reports (Washington, D.C. : 1974) (2003) [Pubmed]
  6. Ultraviolet recall phenomenon following the use of ampicillin. Blanco, J., Manzanedo, L., Gutierrez, M.C., Fuentes, M. Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología. (2002) [Pubmed]
  7. Decreased photodamage and low incidence of non-melanoma skin cancer in 136 sun-exposed caucasian patients with vitiligo. Schallreuter, K.U., Tobin, D.J., Panske, A. Dermatology (Basel) (2002) [Pubmed]
  8. The skin we are in--knowledge and practices regarding skin cancer in pre-clinical medical students. Gillani, F., Rashid, A., Anis, A., Arif, S., Jamall, A., Iqbal, N., Khan, A. JPMA. The Journal of the Pakistan Medical Association. (2001) [Pubmed]
  9. Prevention campaign against skin cancer. Heinzerling, L.M., Dummer, R., Panizzon, R.G., Bloch, P.H., Barbezat, R., Burg, G. Dermatology (Basel) (2002) [Pubmed]
WikiGenes - Universities