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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Association between hyperhomocysteinaemia and hypertension in Sri Lankans.

This study examined the relationship between homocysteine and its metabolites, and hypertension in a cohort of Sri Lankan patients with essential hypertension. Serum homocysteine, cysteine, cysteinylglycine and glutathione were measured in 86 patients with a diagnosis of essential hypertension and compared with those of an age- and sex-matched control group. Patients with hypertension had significantly higher mean serum concentrations of homocysteine, cysteine and cysteinylglycine. The odds ratio for hypertension for those with a mean serum homocysteine concentration above 18 mumol/l was 2. 8. Hyperhomocysteinaemia is a risk factor for hypertension in Sri Lankans and can lead to a threefold increase in risk.[1]

References

  1. Association between hyperhomocysteinaemia and hypertension in Sri Lankans. Mendis, S., Athauda, S.B., Naser, M., Takahashi, K. J. Int. Med. Res. (1999) [Pubmed]
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