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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

False-positive magnetic resonance image in the diagnosis of small acoustic neuroma.

A patient presented with sudden hearing loss on her first visit to our department. Gadolinium-DTPA-enhanced magnetic resonance imaging (MRI) of the posterior cranial fossa portrayed an intracanalicular tumour image (2-3 mm), and the pure tone average (PTA) and speech discrimination score (SDS) values were 65 dB and 60 per cent, respectively. Surgical intervention to remove the suspected tumour was scheduled by the translabyrinthine approach. Intracanalicular observations by the retrolabyrinthine approach revealed limited oedema on the inferior vestibular nerve with vascular dilation. The tumour image disappeared two years after the operation. Surgical findings and the post-operative course advocate that gadolinium-DTPA-enriched MRI image of an intracanalicular lesion such as arachnoiditis might produce a false-positive result.[1]


  1. False-positive magnetic resonance image in the diagnosis of small acoustic neuroma. Maeta, M., Saito, R., Nameki, H. The Journal of laryngology and otology. (2001) [Pubmed]
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