Disease relevance of Cranial Fossa, Posterior

• A 67-year-old white man with a remote history of a chordoma of the clivus presented with myasthenia gravis [1].
• The approach has since been used to approach clivus tumors and midline aneurysms of the vertebrobasilar system [2].
• Syringomyelia as a postoperative sequela of the resection of a chordoma of the clivus: case report [3].
• Drop metastases in a patient with a chondroid chordoma of the clivus [4].
• Two patients, a 12-year-old girl and an 8-year-old boy, with congenital craniovertebral anomaly and Klippel-Feil syndrome also had a posterior cranial fossa dermoid [5].

High impact information on Cranial Fossa, Posterior

• First cytogenetic study of a recurrent familial chordoma of the clivus [6].
• Infiltration of the clivus by the tumor and LDH greater than 410 U/L are the two independent and useful prognostic factors in patients with locoregionally advanced NPC who were treated with CCRT [7].
• METHODS: Twenty-one normal children 3 to 11.5 years old underwent computed tomographic examinations from the lower clivus to the base of C3 in various head positions during axial rotation [8].
• These modifications consisted of a hemisphenoidotomy, a partial ethmoidectomy, extended sellar floor opening toward the planum sphenoidale or the clivus, enlarged opening of the sphenoid ostium area with ipsilateral removal of the superior turbinate, and a bilateral approach [9].
• Radiologically, there was fusion of C1, C2, and the clivus [10].

Chemical compound and disease context of Cranial Fossa, Posterior

• Following excision of pilocytic astrocytoma, a 12-year-old girl underwent posterior cranial fossa synthetic duraplasty with polyglactin 910 mesh [11].
• Clinical use of lidocaine for control of stroke oedema in the posterior cranial fossa accompanied by acute hydrocephalus [12].
• The lesions in this patient group included metastasis to the cavernous sinus and clivus (3); fibrous dysplasia (2); plasmacytoma of the clivus (2); and 1 patient each with cholesterol granuloma, meningoencephalocele, and recurrent teratoma [13].

Anatomical context of Cranial Fossa, Posterior

• This report describes in a stepwise fashion the surgical anatomy of an approach to the midline and lateral compartments of the skull base (clivus, infralabyrinthine/infratemporal regions) [14].
• After removal of the clivus with a drill, the vertebral and basilar arteries are exposed through a midline dural opening [15].
• The authors report on 16 consecutive patients requiring exposure from clivus through C3 for pathology, including spinal cord compression by rheumatoid pannus, craniovertebral anomalies, and tumor [16].
• The author suggests that a rupture is initiated by the compression of the brain stem against the clivus, whereby the pedunculi are displaced away from each other, and that the rupture naturally continues along the midline vessels to end in the aqueduct [17].
• Gadolinium diethylene-thiamine-pentaacetic acid enhanced T1-weighted magnetic resonance (MR) images showed a homogeneously enhanced mass lesion involving the lower clivus and the foramen magnum [18].

Associations of Cranial Fossa, Posterior with chemical compounds

• We retrospectively reviewed 330 T1-weighted sagittal images, 80 T2-weighted sagittal images, and 83 gadopentetate-dimeglumine-enhanced scans of normal adults to determine the MR appearance of the normal adult clivus [19].
• Similarly, the ability to localize the rostral limit of the clivus that needed to be resected and the caudal extent of C2 that needed to be removed to achieve an adequate decompression helped ensure that the extent of bone removal was appropriately tailored to the patient's anatomy [20].
• Magnetic resonance imaging showed gadolinium enhancement of the soft tissue overlying the clivus and around the odontoid, impinging on the medulla and high cervical cord [21].
• The position offers a view that is approximately coronal to the clivus and tentorium [22].
• This case shows that polyglactin 910 mesh may be ineffective when used for posterior cranial fossa duraplasty in children, although it is considered as valuable as autologous tissue [11].

Gene context of Cranial Fossa, Posterior

• Transoral resection of the dens, the anterior arch of C-1, and the lower clivus does not fully destabilize the spine; however, this operation may potentiate incipient pathological instability [23].
• Clivus chordoma in a child with tuberous sclerosis: CT and MR demonstration [24].
• Primary neoplasms, metastatic tumors, and inflammatory, vascular, and hematopoietic disorders are the most common abnormalities to arise from or directly involve the clivus [25].
• After the first operation, local recurrence and CSF dissemination to the lower clivus occurred within two months [26].
• Axial computerized tomography (CT) scans revealed a C-1 ring fracture, basilar invagination with the dens abutting the clivus, and significant lateral splaying of the C-1 lateral masses [27].

Analytical, diagnostic and therapeutic context of Cranial Fossa, Posterior

• We described our experience with a partial segmented Le Fort I osteotomy added to a transmandibular approach to expose a chordoma of the clivus and left parapharyngeal space [28].
• We report a patient with an intracranial chondroid chordoma, typically involving the clivus, treated by repeated resection, percutaneous transluminal embolisation and radiosurgery [4].
• T classification and clivus margin as risk factors for determining locoregional control by radiotherapy of nasopharyngeal carcinoma [29].
• Immunocytochemistry (ICC) proved to be an essential adjunct in the fine-needle aspiration (FNA) cytological diagnosis of chordoma of the clivus in a 62-year-old woman [30].
• In the present paper we present the case of a 50-year-old Caucasian man affected by chordoma of the clivus, with liver and chest metastases, relapsed after several surgical local excisions, to discuss improvements in therapeutic and imaging techniques [31].

References