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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Pest-managing efficacy of trans-asarone isolated from Daucus carota L. seeds.

The bioactive hexane extract of Daucus carota seed yielded 2,4,5-trimethoxybenzaldehyde (1), oleic acid (2), trans-asarone (3), and geraniol (4). Compounds 1-4 were evaluated for their mosquitocidal, nematicidal, antifeedant, and antimicrobial activities. Only trans-asarone was active in the assays performed, causing 100% mortality to fourth-instar mosquito larvae, Aedes aegyptii, at 200 microg mL(-1) and the nematodes Caenorhabditis elegans and Panagrellus redivivus at 100 microg mL(-1). In feeding trials, trans-asarone also caused significant weight reductions of the caterpillars Helicovarpa zea, Heliothis virescens, and Manduca sexta when incorporated into artificial diet at a concentration of 100 microg mL(-1). Also, it exhibited slight activity at 100 microg mL(-1) against the yeasts Candida albicans, Candida parapsilasis, and Candida kruseii.[1]


  1. Pest-managing efficacy of trans-asarone isolated from Daucus carota L. seeds. Momin, R.A., Nair, M.G. J. Agric. Food Chem. (2002) [Pubmed]
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