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Chemical Compound Review

Chokegard     (Z)-hexadec-11-enal

Synonyms: AC1NSJOX, Hercon disrupt, KB-05747, LS-74869, LMFA06000211, ...
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Disease relevance of Hercon disrupt


Psychiatry related information on Hercon disrupt


High impact information on Hercon disrupt

  • As a test of whether orthologous beta-tubulins from different species are functionally equivalent, the moth Heliothis virescens beta2 homolog was expressed in Drosophila testes [8].
  • By using a combination of genomic sequence analysis and cDNA-library screening, we have cloned various cDNAs of the tobacco budworm Heliothis virescens encoding candidate olfactory receptors [9].
  • The recent commercialization of genetically engineered cotton that constitutively produces an insecticidal protein derived from the biocontrol agent, Bacillus thuringiensis (Bt) has raised concern that we lack data needed to quantify the risk of insect pests such as Heliothis virescens rapidly adapting to this ecologically valuable class of toxins [10].
  • For successful parasitization, the female Campoletis sonorensis endoparasitic wasp injects a polydnavirus into its host, Heliothis virescens, during oviposition [11].
  • In a cross-species study, M. sexta allatostatin also inhibited the corpora allata of adult female Heliothis virescens but had no effect on the activity of corpora allata of adult females of the beetle Tenebrio molitor, the grasshopper Melanoplus sanguinipes, or the cockroach Periplaneta americana [12].

Chemical compound and disease context of Hercon disrupt


Biological context of Hercon disrupt


Anatomical context of Hercon disrupt


Associations of Hercon disrupt with other chemical compounds


Gene context of Hercon disrupt


Analytical, diagnostic and therapeutic context of Hercon disrupt


  1. Broad-spectrum resistance to Bacillus thuringiensis toxins in Heliothis virescens. Gould, F., Martinez-Ramirez, A., Anderson, A., Ferre, J., Silva, F.J., Moar, W.J. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  2. Specificity-determining regions of a lepidopteran-specific insecticidal protein produced by Bacillus thuringiensis. Schnepf, H.E., Tomczak, K., Ortega, J.P., Whiteley, H.R. J. Biol. Chem. (1990) [Pubmed]
  3. Central role of hemocytes in Autographa californica M nucleopolyhedrovirus pathogenesis in Heliothis virescens and Helicoverpa zea. Trudeau, D., Washburn, J.O., Volkman, L.E. J. Virol. (2001) [Pubmed]
  4. Synthesis of biologically active influenza virus hemagglutinin in insect larvae. Kuroda, K., Gröner, A., Frese, K., Drenckhahn, D., Hauser, C., Rott, R., Doerfler, W., Klenk, H.D. J. Virol. (1989) [Pubmed]
  5. Ecdysone agonist inducible transcription in transgenic tobacco plants. Martinez, A., Sparks, C., Hart, C.A., Thompson, J., Jepson, I. Plant J. (1999) [Pubmed]
  6. Mating in Heliothis virescens: transfer of juvenile hormone during copulation by male to female and stimulation of biosynthesis of endogenous juvenile hormone. Park, Y.I., Shu, S., Ramaswamy, S.B., Srinivasan, A. Arch. Insect Biochem. Physiol. (1998) [Pubmed]
  7. Plant phenolics as dietary antioxidants for herbivorous insects: a test with genetically modified tobacco. Johnson, K.S., Felton, G.W. J. Chem. Ecol. (2001) [Pubmed]
  8. Microtubule architecture specified by a beta-tubulin isoform. Raff, E.C., Fackenthal, J.D., Hutchens, J.A., Hoyle, H.D., Turner, F.R. Science (1997) [Pubmed]
  9. Genes encoding candidate pheromone receptors in a moth (Heliothis virescens). Krieger, J., Grosse-Wilde, E., Gohl, T., Dewer, Y.M., Raming, K., Breer, H. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  10. Initial frequency of alleles for resistance to Bacillus thuringiensis toxins in field populations of Heliothis virescens. Gould, F., Anderson, A., Jones, A., Sumerford, D., Heckel, D.G., Lopez, J., Micinski, S., Leonard, R., Laster, M. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  11. Structure and evolutionary implications of a "cysteine-rich" Campoletis sonorensis polydnavirus gene family. Dib-Hajj, S.D., Webb, B.A., Summers, M.D. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  12. Identification of an allatostatin from the tobacco hornworm Manduca sexta. Kramer, S.J., Toschi, A., Miller, C.A., Kataoka, H., Quistad, G.B., Li, J.P., Carney, R.L., Schooley, D.A. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  13. Mutations at domain II, loop 3, of Bacillus thuringiensis CryIAa and CryIAb delta-endotoxins suggest loop 3 is involved in initial binding to lepidopteran midguts. Rajamohan, F., Hussain, S.R., Cotrill, J.A., Gould, F., Dean, D.H. J. Biol. Chem. (1996) [Pubmed]
  14. Effects of diet-age and streptomycin on virulence of Autographa californica M nucleopolyhedrovirus against the tobacco budworm. Hoover, K., Schultz, C.M., Lane, S.S., Bonning, B.C., Hammock, B.D., Duffey, S.S. J. Invertebr. Pathol. (1997) [Pubmed]
  15. Isolation and sequencing of insecticidal peptides from the primitive hunting spider, Plectreurys tristis (Simon). Quistad, G.B., Skinner, W.S. J. Biol. Chem. (1994) [Pubmed]
  16. Characterization of two Autographa californica nucleopolyhedrovirus proteins, Ac145 and Ac150, which affect oral infectivity in a host-dependent manner. Lapointe, R., Popham, H.J., Straschil, U., Goulding, D., O'Reilly, D.R., Olszewski, J.A. J. Virol. (2004) [Pubmed]
  17. Early synthesis of budded virus envelope fusion protein GP64 enhances Autographa californica multicapsid nucleopolyhedrovirus virulence in orally infected Heliothis virescens. Washburn, J.O., Chan, E.Y., Volkman, L.E., Aumiller, J.J., Jarvis, D.L. J. Virol. (2003) [Pubmed]
  18. Key disulfide bonds in an insect hormone binding protein: cDNA cloning of a juvenile hormone binding protein of Heliothis virescens and ligand binding by native and mutant forms. Wojtasek, H., Prestwich, G.D. Biochemistry (1995) [Pubmed]
  19. Isolation and identification of paralytic peptides from hemolymph of the lepidopteran insects Manduca sexta, Spodoptera exigua, and Heliothis virescens. Skinner, W.S., Dennis, P.A., Li, J.P., Summerfelt, R.M., Carney, R.L., Quistad, G.B. J. Biol. Chem. (1991) [Pubmed]
  20. Role of domain II, loop 2 residues of Bacillus thuringiensis CryIAb delta-endotoxin in reversible and irreversible binding to Manduca sexta and Heliothis virescens. Rajamohan, F., Cotrill, J.A., Gould, F., Dean, D.H. J. Biol. Chem. (1996) [Pubmed]
  21. Heliothis virescens and Manduca sexta lipid rafts are involved in Cry1A toxin binding to the midgut epithelium and subsequent pore formation. Zhuang, M., Oltean, D.I., Gómez, I., Pullikuth, A.K., Soberón, M., Bravo, A., Gill, S.S. J. Biol. Chem. (2002) [Pubmed]
  22. Expression of 65- and 67-kilodalton heat-regulated proteins and a 70-kilodalton heat shock cognate protein of Leishmania donovani in macrophages. Rey-Ladino, J.A., Reiner, N.E. Infect. Immun. (1993) [Pubmed]
  23. Characterization of the I{kappa}B-like gene family in polydnaviruses associated with wasps belonging to different Braconid subfamilies. Falabella, P., Varricchio, P., Provost, B., Espagne, E., Ferrarese, R., Grimaldi, A., de Eguileor, M., Fimiani, G., Ursini, M.V., Malva, C., Drezen, J.M., Pennacchio, F. J. Gen. Virol. (2007) [Pubmed]
  24. A specific affinity reagent to distinguish aldehyde dehydrogenases and oxidases. Enzymes catalyzing aldehyde oxidation in an adult moth. Tasayco, M.L., Prestwich, G.D. J. Biol. Chem. (1990) [Pubmed]
  25. Analogous recognition of phospholipids by insect phagocytes and mammalian macrophages. Ratner, S., Schroit, A.J., Vinson, S.B., Fidler, I.J. Proc. Soc. Exp. Biol. Med. (1986) [Pubmed]
  26. Identification of methyl farnesoate from in vitro culture of the retrocerebral complex of adult females of the moth, Heliothis virescens (Lepidoptera: Noctuidae) and its conversion to juvenile hormone III. Teal, P.E., Proveaux, A.T. Arch. Insect Biochem. Physiol. (2006) [Pubmed]
  27. Role of integrin beta1-like protein in proliferation and differentiation of cultured stem cells from midgut of Heliothis virescens. Loeb, M.J. Arch. Insect Biochem. Physiol. (2006) [Pubmed]
  28. Novel putative nicotinic acetylcholine receptor subunit genes, Dalpha5, Dalpha6 and Dalpha7, in Drosophila melanogaster identify a new and highly conserved target of adenosine deaminase acting on RNA-mediated A-to-I pre-mRNA editing. Grauso, M., Reenan, R.A., Culetto, E., Sattelle, D.B. Genetics (2002) [Pubmed]
  29. Promoter analysis of a cysteine-rich Campoletis sonorensis polydnavirus gene. Cuit, L., Webb, B.A. J. Gen. Virol. (1997) [Pubmed]
  30. Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity. Lamberty, M., Ades, S., Uttenweiler-Joseph, S., Brookhart, G., Bushey, D., Hoffmann, J.A., Bulet, P. J. Biol. Chem. (1999) [Pubmed]
  31. Arrestin-subtypes in insect antennae. Raming, K., Freitag, J., Krieger, J., Breer, H. Cell. Signal. (1993) [Pubmed]
  32. Deletion of pe38 attenuates AcMNPV genome replication, budded virus production, and virulence in heliothis virescens. Milks, M.L., Washburn, J.O., Willis, L.G., Volkman, L.E., Theilmann, D.A. Virology (2003) [Pubmed]
  33. Digital atlases of the antennal lobe in two species of tobacco budworm moths, the Oriental Helicoverpa assulta (male) and the American Heliothis virescens (male and female). Berg, B.G., Galizia, C.G., Brandt, R., Mustaparta, H. J. Comp. Neurol. (2002) [Pubmed]
  34. The plant sesquiterpene germacrene D specifically activates a major type of antennal receptor neuron of the tobacco budworm moth Heliothis virescens. Røstelien, T., Borg-Karlson, A.K., Fäldt, J., Jacobsson, U., Mustaparta, H. Chem. Senses (2000) [Pubmed]
  35. Immunocytochemical, electrophoresis, and immunoblot analysis of Heliothis virescens gap junctions isolated in the presence and absence of protease inhibitors. Ryerse, J.S. Cell Tissue Res. (1995) [Pubmed]
  36. Purification and characterization of lysozyme from hemolymph of Heliothis virescens larvae. Lockey, T.D., Ourth, D.D. Biochem. Biophys. Res. Commun. (1996) [Pubmed]
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