- Despite in vitro increase in cyclic guanosine monophosphate concentrations, intracarotid nitroprusside fails to augment cerebral blood flow of healthy baboons. Joshi, S., Hartl, R., Sun, L.S., Libow, A.D., Wang, M., Pile-Spellman, J., Young, W.L., Connolly, E.S., Hirshman, C.A. Anesthesiology (2003)