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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Low micromolar human A-FABP inhibitors were found by utilizing a fluorescence polarization assay, X-raycrystallography and modeling. The carbazole- and indole-based inhibitors displayed approximately 10-fold preferences over human H-FABP and E-FABP, and are highly selective against I-FABP. This communication describes the SAR for drug-like synthetic inhibitors of human A-FABP.[1]
