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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Pulmonary and paradoxical embolism in protein C and S deficient patient.

We document the case of a 67-year-old woman who presented with a history of right upper quadrant anopia, dyspnea, hypoxemia, and a systolic murmur. An intracardiac embolus wedged at a patent foramen ovale was successfully removed by resecting the atrial septum along with a pulmonary embolectomy on cardiopulmonary bypass. We review the literature with specific focus on the pathogenesis and acute treatment options of this life-threatening occurrence.[1]


  1. Pulmonary and paradoxical embolism in protein C and S deficient patient. Kumar, S., Khan, I., Milton, R., Ali, A.A., O'Regan, D.J. Ann. Thorac. Surg. (2005) [Pubmed]
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