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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Efficient internal pallidal stimulation in Gilles de la Tourette syndrome: a case report.

The usefulness of deep brain stimulation (DBS) of thalamic nuclei in Gilles de la Tourette syndrome ( GTS) has recently been advocated. We report on a 14-month follow-up study of a patient with intractable GTS in whom bilateral DBS of the internal globus pallidus was carried out. Tic frequency per minute decreased by 73% in the postoperative phase and in particular the vocal tics became less intense. Pronation/ supination bradykinesia of the left extremities was a well-tolerated, permanent side effect. Pallidal DBS could become a valuable rescue therapy for otherwise intractable GTS.[1]

References

  1. Efficient internal pallidal stimulation in Gilles de la Tourette syndrome: a case report. Diederich, N.J., Kalteis, K., Stamenkovic, M., Pieri, V., Alesch, F. Mov. Disord. (2005) [Pubmed]
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