The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)


Camalexin (3-thiazol-2'-yl-indole) is the characteristic phytoalexin of Arabidopsis thaliana, which is induced by a great variety of plant pathogens. While particular pathogens, as well as a human tumour cell line, were growth inhibited by camalexin, some fungi show resistance due to active degradation. Camalexin originates from tryptophan and its biosynthesis involves the cytochrome P450 enzymes CYP79B2 and CYP71B15 (PAD3). Camalexin induction is a complex process, for which triggering by reactive oxygen species (ROS), salicylic acid signalling, and the glutathione status are important. Targets of the signalling cascade are the tryptophan and camalexin biosynthetic genes, which are strongly transcriptionally upregulated at the sites of pathogen infection. The important knowledge on camalexin, which is reviewed in this paper, will help to establish camalexin as a model for the investigation of the significance of phytoalexins in response pathogen challenge.[1]


  1. Camalexin. Glawischnig, E. Phytochemistry (2007) [Pubmed]
WikiGenes - Universities