- The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Glas, J., Konrad, A., Schmechel, S., Dambacher, J., Seiderer, J., Schroff, F., Wetzke, M., Roeske, D., Török, H.P., Tonenchi, L., Pfennig, S., Haller, D., Griga, T., Klein, W., Epplen, J.T., Folwaczny, C., Lohse, P., Göke, B., Ochsenkühn, T., Mussack, T., Folwaczny, M., Müller-Myhsok, B., Brand, S. Am. J. Gastroenterol. (2008)