The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Crohn Disease

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Crohn Disease


Psychiatry related information on Crohn Disease


High impact information on Crohn Disease


Chemical compound and disease context of Crohn Disease


Biological context of Crohn Disease


Anatomical context of Crohn Disease


Gene context of Crohn Disease


Analytical, diagnostic and therapeutic context of Crohn Disease


  1. A placebo-controlled, double-blind, randomized trial of cyclosporine therapy in active chronic Crohn's disease. Brynskov, J., Freund, L., Rasmussen, S.N., Lauritsen, K., de Muckadell, O.S., Williams, N., MacDonald, A.S., Tanton, R., Molina, F., Campanini, M.C. N. Engl. J. Med. (1989) [Pubmed]
  2. Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study. Present, D.H., Korelitz, B.I., Wisch, N., Glass, J.L., Sachar, D.B., Pasternack, B.S. N. Engl. J. Med. (1980) [Pubmed]
  3. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Garcia-Zepeda, E.A., Rothenberg, M.E., Ownbey, R.T., Celestin, J., Leder, P., Luster, A.D. Nat. Med. (1996) [Pubmed]
  4. Processing of tumour necrosis factor-alpha precursor by metalloproteinases. Gearing, A.J., Beckett, P., Christodoulou, M., Churchill, M., Clements, J., Davidson, A.H., Drummond, A.H., Galloway, W.A., Gilbert, R., Gordon, J.L. Nature (1994) [Pubmed]
  5. CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation. Suzuki, A., Hanada, T., Mitsuyama, K., Yoshida, T., Kamizono, S., Hoshino, T., Kubo, M., Yamashita, A., Okabe, M., Takeda, K., Akira, S., Matsumoto, S., Toyonaga, A., Sata, M., Yoshimura, A. J. Exp. Med. (2001) [Pubmed]
  6. Curcumin: getting back to the roots. Shishodia, S., Sethi, G., Aggarwal, B.B. Ann. N. Y. Acad. Sci. (2005) [Pubmed]
  7. Genetic variation in DLG5 is associated with inflammatory bowel disease. Stoll, M., Corneliussen, B., Costello, C.M., Waetzig, G.H., Mellgard, B., Koch, W.A., Rosenstiel, P., Albrecht, M., Croucher, P.J., Seegert, D., Nikolaus, S., Hampe, J., Lengauer, T., Pierrou, S., Foelsch, U.R., Mathew, C.G., Lagerstrom-Fermer, M., Schreiber, S. Nat. Genet. (2004) [Pubmed]
  8. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Peltekova, V.D., Wintle, R.F., Rubin, L.A., Amos, C.I., Huang, Q., Gu, X., Newman, B., Van Oene, M., Cescon, D., Greenberg, G., Griffiths, A.M., St George-Hyslop, P.H., Siminovitch, K.A. Nat. Genet. (2004) [Pubmed]
  9. A comparison of budesonide and mesalamine for active Crohn's disease. International Budesonide-Mesalamine Study Group. Thomsen, O.O., Cortot, A., Jewell, D., Wright, J.P., Winter, T., Veloso, F.T., Vatn, M., Persson, T., Pettersson, E. N. Engl. J. Med. (1998) [Pubmed]
  10. Methotrexate for Crohn's disease. Korelitz, B.I., Present, D.H. N. Engl. J. Med. (1995) [Pubmed]
  11. A comparison of budesonide with prednisolone for active Crohn's disease. Rutgeerts, P., Löfberg, R., Malchow, H., Lamers, C., Olaison, G., Jewell, D., Danielsson, A., Goebell, H., Thomsen, O.O., Lorenz-Meyer, H. N. Engl. J. Med. (1994) [Pubmed]
  12. Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators. Feagan, B.G., Rochon, J., Fedorak, R.N., Irvine, E.J., Wild, G., Sutherland, L., Steinhart, A.H., Greenberg, G.R., Gillies, R., Hopkins, M. N. Engl. J. Med. (1995) [Pubmed]
  13. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Ogura, Y., Bonen, D.K., Inohara, N., Nicolae, D.L., Chen, F.F., Ramos, R., Britton, H., Moran, T., Karaliuskas, R., Duerr, R.H., Achkar, J.P., Brant, S.R., Bayless, T.M., Kirschner, B.S., Hanauer, S.B., Nuñez, G., Cho, J.H. Nature (2001) [Pubmed]
  14. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Hugot, J.P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C.A., Gassull, M., Binder, V., Finkel, Y., Cortot, A., Modigliani, R., Laurent-Puig, P., Gower-Rousseau, C., Macry, J., Colombel, J.F., Sahbatou, M., Thomas, G. Nature (2001) [Pubmed]
  15. Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study. Hampe, J., Grebe, J., Nikolaus, S., Solberg, C., Croucher, P.J., Mascheretti, S., Jahnsen, J., Moum, B., Klump, B., Krawczak, M., Mirza, M.M., Foelsch, U.R., Vatn, M., Schreiber, S. Lancet (2002) [Pubmed]
  16. The c-insertion mutation of the NOD2 gene is associated with fistulizing and fibrostenotic phenotypes in Crohn's disease. Radlmayr, M., Török, H.P., Martin, K., Folwaczny, C. Gastroenterology (2002) [Pubmed]
  17. Enhanced local production of complement components in the small intestines of patients with Crohn's disease. Ahrenstedt, O., Knutson, L., Nilsson, B., Nilsson-Ekdahl, K., Odlind, B., Hällgren, R. N. Engl. J. Med. (1990) [Pubmed]
  18. Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. Dubucquoi, S., Desreumaux, P., Janin, A., Klein, O., Goldman, M., Tavernier, J., Capron, A., Capron, M. J. Exp. Med. (1994) [Pubmed]
  19. Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody. Podolsky, D.K., Lobb, R., King, N., Benjamin, C.D., Pepinsky, B., Sehgal, P., deBeaumont, M. J. Clin. Invest. (1993) [Pubmed]
  20. Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease. Kosiewicz, M.M., Nast, C.C., Krishnan, A., Rivera-Nieves, J., Moskaluk, C.A., Matsumoto, S., Kozaiwa, K., Cominelli, F. J. Clin. Invest. (2001) [Pubmed]
  21. Changes in size, subclass, and metabolic properties of serum immunoglobulin A in liver diseases and in other diseases with high serum immunoglobulin A. Delacroix, D.L., Elkom, K.B., Geubel, A.P., Hodgson, H.F., Dive, C., Vaerman, J.P. J. Clin. Invest. (1983) [Pubmed]
  22. Distinct cytokine patterns in early and chronic ileal lesions of Crohn's disease. Desreumaux, P., Brandt, E., Gambiez, L., Emilie, D., Geboes, K., Klein, O., Ectors, N., Cortot, A., Capron, M., Colombel, J.F. Gastroenterology (1997) [Pubmed]
  23. Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease. Van den Brande, J.M., Braat, H., van den Brink, G.R., Versteeg, H.H., Bauer, C.A., Hoedemaeker, I., van Montfrans, C., Hommes, D.W., Peppelenbosch, M.P., van Deventer, S.J. Gastroenterology (2003) [Pubmed]
  24. Tumor necrosis factor alpha blockade restores growth hormone signaling in murine colitis. DiFedele, L.M., He, J., Bonkowski, E.L., Han, X., Held, M.A., Bohan, A., Menon, R.K., Denson, L.A. Gastroenterology (2005) [Pubmed]
  25. Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD. Vermeire, S., Pierik, M., Hlavaty, T., Claessens, G., van Schuerbeeck, N., Joossens, S., Ferrante, M., Henckaerts, L., Bueno de Mesquita, M., Vlietinck, R., Rutgeerts, P. Gastroenterology (2005) [Pubmed]
  26. Characteristics of intestinal dendritic cells in inflammatory bowel diseases. Hart, A.L., Al-Hassi, H.O., Rigby, R.J., Bell, S.J., Emmanuel, A.V., Knight, S.C., Kamm, M.A., Stagg, A.J. Gastroenterology (2005) [Pubmed]
  27. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Hampe, J., Franke, A., Rosenstiel, P., Till, A., Teuber, M., Huse, K., Albrecht, M., Mayr, G., De La Vega, F.M., Briggs, J., Günther, S., Prescott, N.J., Onnie, C.M., Häsler, R., Sipos, B., Fölsch, U.R., Lengauer, T., Platzer, M., Mathew, C.G., Krawczak, M., Schreiber, S. Nat. Genet. (2007) [Pubmed]
  28. A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5. Prescott, N.J., Fisher, S.A., Franke, A., Hampe, J., Onnie, C.M., Soars, D., Bagnall, R., Mirza, M.M., Sanderson, J., Forbes, A., Mansfield, J.C., Lewis, C.M., Schreiber, S., Mathew, C.G. Gastroenterology (2007) [Pubmed]
  29. A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators. Feagan, B.G., Fedorak, R.N., Irvine, E.J., Wild, G., Sutherland, L., Steinhart, A.H., Greenberg, G.R., Koval, J., Wong, C.J., Hopkins, M., Hanauer, S.B., McDonald, J.W. N. Engl. J. Med. (2000) [Pubmed]
  30. CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. Tiede, I., Fritz, G., Strand, S., Poppe, D., Dvorsky, R., Strand, D., Lehr, H.A., Wirtz, S., Becker, C., Atreya, R., Mudter, J., Hildner, K., Bartsch, B., Holtmann, M., Blumberg, R., Walczak, H., Iven, H., Galle, P.R., Ahmadian, M.R., Neurath, M.F. J. Clin. Invest. (2003) [Pubmed]
  31. Malabsorption of cyclosporin in renal transplant recipient with Crohn's disease. Williams, J.D., Salaman, J.R., Griffin, P.J., Hillis, A.N., Ross, W., Williams, G.T. Lancet (1987) [Pubmed]
  32. Mucosal expression by B7-positive cells of the 60-kilodalton heat-shock protein in inflammatory bowel disease. Peetermans, W.E., D'Haens, G.R., Ceuppens, J.L., Rutgeerts, P., Geboes, K. Gastroenterology (1995) [Pubmed]
  33. Home parenteral nutrition in children with Crohn's disease. Strobel, C.T. Gastroenterology (1979) [Pubmed]
WikiGenes - Universities