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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Sakagami, H. et al.

Hiroshi Sakagami, Kazue Satoh, Haruka Fukamachi, Takeshi Ikarashi, Ai Shimizu, Kazuyoshi Yano, Taisei Kanamoto, Shigemi Terakubo, Hideki Nakashima, Hideo Hasegawa, Akiko Nomura, Katsuaki Utsumi, Masaji Yamamoto, Yuuichi Maeda, Kenji Osawa,

Anti-HIV and vitamin C-synergized radical scavenging activity of cacao husk lignin fractions.

Cacao husk lignin fractions, prepared by acid precipitation and 50% ethanol precipitation showed unexpectedly higher anti-human immunodeficiency virus (HIV) activity, as compared with the corresponding fractions from the cacao mass, amounting to the level comparable with that of popular anti-HIV compounds. The cacao husk lignin fractions also showed anti-influenza virus activity, but did not show antibacterial activity. The cacao husk lignin fractions synergistically enhanced the superoxide anion and hydroxyl radical scavenging activity of vitamin C. The cacao husk lignin fractions stimulated nitric oxide generation by mouse macrophage-like cells, to a level higher than that attained by lipopolysaccharide (LPS). The present study suggests the functionality of cacao husk lignin fractions as complementary alternative medicine.[1]

References

Anti-HIV and vitamin C-synergized radical scavenging activity of cacao husk lignin fractions. Sakagami, H., Satoh, K., Fukamachi, H., Ikarashi, T., Shimizu, A., Yano, K., Kanamoto, T., Terakubo, S., Nakashima, H., Hasegawa, H., Nomura, A., Utsumi, K., Yamamoto, M., Maeda, Y., Osawa, K. In. Vivo (2008) [Pubmed]

Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg