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MeSH Review

Complementary Therapies

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Disease relevance of Complementary Therapies


Psychiatry related information on Complementary Therapies


High impact information on Complementary Therapies


Chemical compound and disease context of Complementary Therapies


Biological context of Complementary Therapies


Anatomical context of Complementary Therapies

  • Advances in cyclooxygenase inhibition selectivity, alternative medicine, and progress in the identification of nonopioid pain receptors and the development of products to target them are just a few of changes that have altered the way clinicians think about treating pain [22].
  • Despite the inherent difficulties in stimulating melanocytes to repigment vitiliginous lesions, a variety of medical, surgical, and adjunctive/alternative therapies benefit innumerable patients with vitiligo [23].

Associations of Complementary Therapies with chemical compounds

  • The National Heart, Lung, and Blood Institute and the National Center for Complementary and Alternative Medicine recently cosponsored a workshop on the use of complementary and alternative medicine (CAM) in cardiovascular, lung, and blood research [24].
  • The lack of approved alternative therapies for T. vaginalis treatment means that higher and sometimes toxic doses of metronidazole are the only option for patients with resistant disease [25].
  • Although symptomatic therapies to substitute for the missing neurotransmitter dopamine are efficient at the early stages of the disease, the goal is to find alternative therapies which could protect dopaminergic neurons from the degenerative process [26].
  • BACKGROUND: Dose-adjusted warfarin is beneficial as thromboprophylaxis in AF, but potentially serious side effects and regular monitoring leave room for alternative therapies [27].
  • Integrating complementary medicine into cardiovascular medicine. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents (Writing Committee to Develop an Expert Consensus Document on Complementary and Integrative Medicine) [28].

Gene context of Complementary Therapies

  • The ability to noninvasively monitor COX-2 expression with molecular imaging probes will provide a corresponding advance in diagnosing COX-2-based disease, monitoring progression of such diseases, and evaluating alternative therapies [29].
  • Together, these data further support a role for beta-synuclein in regulating the conformational state of alpha-synuclein and suggest that this gene transfer approach might have potential for the development of alternative therapies for PD and DLB [30].
  • Although GDNF remains a powerful neurotrophin, the search for alternative therapies based on alternative and complementary mechanisms of action to GDNF is warranted [31].
  • Complementary medicine use before and 1 year following genetic testing for BRCA1/2 mutations [32].
  • This study describes use of complementary and alternative medicine among children with ADHD or at risk of having ADHD and explores possible predictors of use of such treatments [33].

Analytical, diagnostic and therapeutic context of Complementary Therapies


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  2. A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen. Goetz, M.P., Suman, V.J., Ingle, J.N., Nibbe, A.M., Visscher, D.W., Reynolds, C.A., Lingle, W.L., Erlander, M., Ma, X.J., Sgroi, D.C., Perez, E.A., Couch, F.J. Clin. Cancer Res. (2006) [Pubmed]
  3. Foscarnet therapy for acyclovir-resistant mucocutaneous herpes simplex virus infection in 26 AIDS patients: preliminary data. Safrin, S., Assaykeen, T., Follansbee, S., Mills, J. J. Infect. Dis. (1990) [Pubmed]
  4. Early versus delayed treatment of HIV infection. Zidovudine should be given before symptoms develop. Richman, D.D., Havlir, D. Drugs (1995) [Pubmed]
  5. Challenging the platinum combinations: docetaxel (Taxotere) combined with gemcitabine or vinorelbine in non-small cell lung cancer. Georgoulias, V., Scagliotti, G., Miller, V., Eckardt, J., Douillard, J.Y., Manegold, C. Semin. Oncol. (2001) [Pubmed]
  6. New concepts in mood stabilization: evidence for the effectiveness of valproate and lamotrigine. Bowden, C.L. Neuropsychopharmacology (1998) [Pubmed]
  7. Hyperalimentation in cancer. Souba, W.W., Copeland, E.M. CA: a cancer journal for clinicians. (1989) [Pubmed]
  8. Complementary and alternative medicine in neurology: hype, hope and hazards. Ernst, E. Trends Neurosci. (2002) [Pubmed]
  9. Alternative therapies getting notice through Best Case Series Program. Vanchieri, C. J. Natl. Cancer Inst. (2000) [Pubmed]
  10. Immunotherapeutic strategies for hepatocellular carcinoma. Butterfield, L.H. Gastroenterology (2004) [Pubmed]
  11. Forty years of lithium treatment. Schou, M. Arch. Gen. Psychiatry (1997) [Pubmed]
  12. Heparin-induced thrombocytopenia and arterial thrombosis: alternative therapies. Cola, C., Ansell, J. Am. Heart J. (1990) [Pubmed]
  13. Treatment of diencephalic syndrome with chemotherapy: growth, tumor response, and long term control. Gropman, A.L., Packer, R.J., Nicholson, H.S., Vezina, L.G., Jakacki, R., Geyer, R., Olson, J.M., Phillips, P., Needle, M., Broxson, E.H., Reaman, G., Finlay, J. Cancer (1998) [Pubmed]
  14. Tetracycline, metronidazole and amoxicillin-metronidazole combinations in proton pump inhibitor-based triple therapies are equally effective as alternative therapies against Helicobacter pylori infection. Matsushima, M., Suzuki, T., Kurumada, T., Watanabe, S., Watanabe, K., Kobayashi, K., Deguchi, R., Masui, A., Takagi, A., Shirai, T., Muraoka, H., Kobayashi, I., Mine, T. J. Gastroenterol. Hepatol. (2006) [Pubmed]
  15. Costs and effectiveness of ximelagatran for stroke prophylaxis in chronic atrial fibrillation. O'Brien, C.L., Gage, B.F. JAMA (2005) [Pubmed]
  16. Norfloxacin in the eradication of enteric infections in AIDS patients. Heseltine, P.N., Causey, D.M., Appleman, M.D., Corrado, M.L., Leedom, J.M. European journal of cancer & clinical oncology. (1988) [Pubmed]
  17. New approaches to the therapy of mild hypertension. Kaplan, N.M. Am. J. Cardiol. (1983) [Pubmed]
  18. Effect of therapy on infertile couples with antisperm antibodies. Smarr, S.C., Wing, R., Hammond, M.G. Am. J. Obstet. Gynecol. (1988) [Pubmed]
  19. Fish oil interaction with warfarin. Buckley, M.S., Goff, A.D., Knapp, W.E. The Annals of pharmacotherapy. (2004) [Pubmed]
  20. Treatment options for extended-spectrum beta-lactamase-producers. Essack, S.Y. FEMS Microbiol. Lett. (2000) [Pubmed]
  21. Alternative therapies for male and female sexual dysfunction. Aung, H.H., Dey, L., Rand, V., Yuan, C.S. Am. J. Chin. Med. (2004) [Pubmed]
  22. Pain management in older adults: prevention and treatment. Gloth, F.M. Journal of the American Geriatrics Society. (2001) [Pubmed]
  23. Vitiligo. An overview of therapeutic approaches. Grimes, P.E. Dermatologic clinics. (1993) [Pubmed]
  24. State of complementary and alternative medicine in cardiovascular, lung, and blood research: executive summary of a workshop. Lin, M.C., Nahin, R., Gershwin, M.E., Longhurst, J.C., Wu, K.K. Circulation (2001) [Pubmed]
  25. Treatment of infections caused by metronidazole-resistant Trichomonas vaginalis. Cudmore, S.L., Delgaty, K.L., Hayward-McClelland, S.F., Petrin, D.P., Garber, G.E. Clin. Microbiol. Rev. (2004) [Pubmed]
  26. Sustained delivery of GDNF: towards a treatment for Parkinson's disease. Zurn, A.D., Widmer, H.R., Aebischer, P. Brain Res. Brain Res. Rev. (2001) [Pubmed]
  27. A prospective randomized trial of aspirin-clopidogrel combination therapy and dose-adjusted warfarin on indices of thrombogenesis and platelet activation in atrial fibrillation. Kamath, S., Blann, A.D., Chin, B.S., Lip, G.Y. J. Am. Coll. Cardiol. (2002) [Pubmed]
  28. Integrating complementary medicine into cardiovascular medicine. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents (Writing Committee to Develop an Expert Consensus Document on Complementary and Integrative Medicine). Vogel, J.H., Bolling, S.F., Costello, R.B., Guarneri, E.M., Krucoff, M.W., Longhurst, J.C., Olshansky, B., Pelletier, K.R., Tracy, C.M., Vogel, R.A., Vogel, R.A., Abrams, J., Anderson, J.L., Bates, E.R., Brodie, B.R., Grines, C.L., Danias, P.G., Gregoratos, G., Hlatky, M.A., Hochman, J.S., Kaul, S., Lichtenberg, R.C., Lindner, J.R., O'Rourke, R.A., Pohost, G.M., Schofield, R.S., Shubrooks, S.J., Tracy, C.M., Winters, W.L. J. Am. Coll. Cardiol. (2005) [Pubmed]
  29. Cyclooxygenase 2 (COX-2) as a target for therapy and noninvasive imaging. Herschman, H.R., Talley, J.J., DuBois, R. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. (2003) [Pubmed]
  30. An antiaggregation gene therapy strategy for Lewy body disease utilizing beta-synuclein lentivirus in a transgenic model. Hashimoto, M., Rockenstein, E., Mante, M., Crews, L., Bar-On, P., Gage, F.H., Marr, R., Masliah, E. Gene Ther. (2004) [Pubmed]
  31. Neuronal expression of the transcription factor Gli1 using the Talpha1 alpha-tubulin promoter is neuroprotective in an experimental model of Parkinson's disease. Suwelack, D., Hurtado-Lorenzo, A., Millan, E., Gonzalez-Nicolini, V., Wawrowsky, K., Lowenstein, P.R., Castro, M.G. Gene Ther. (2004) [Pubmed]
  32. Complementary medicine use before and 1 year following genetic testing for BRCA1/2 mutations. Digianni, L.M., Rue, M., Emmons, K., Garber, J.E. Cancer Epidemiol. Biomarkers Prev. (2006) [Pubmed]
  33. Use of complementary and alternative medicine for symptoms of attention-deficit hyperactivity disorder. Bussing, R., Zima, B.T., Gary, F.A., Garvan, C.W. Psychiatric services (Washington, D.C.) (2002) [Pubmed]
  34. The use of alternative medical therapies in patients with systemic lupus erythematosus. Trination Study Group. Moore, A.D., Petri, M.A., Manzi, S., Isenberg, D.A., Gordon, C., Senécal, J.L., St Pierre, Y., Joseph, L., Penrod, J., Fortin, P.R., Sutcliffe, N., Goulet, J.R., Choquette, D., Grodzicky, T., Esdaile, J.M., Clarke, A.E. Arthritis Rheum. (2000) [Pubmed]
  35. Prevalence of complementary and alternative medicine use: state-specific estimates from the 2001 Behavioral Risk Factor Surveillance System. Rafferty, A.P., McGee, H.B., Miller, C.E., Reyes, M. American journal of public health. (2002) [Pubmed]
  36. A systematic review of nonpharmacological and nonsurgical therapies for gastroesophageal reflux in infants. Carroll, A.E., Garrison, M.M., Christakis, D.A. Archives of pediatrics & adolescent medicine. (2002) [Pubmed]
  37. Clinical link between MHC class II haplotype and interferon-beta (IFN-beta) immunogenicity. Barbosa, M.D., Vielmetter, J., Chu, S., Smith, D.D., Jacinto, J. Clin. Immunol. (2006) [Pubmed]
  38. Unproven (questionable) dietary and nutritional methods in cancer prevention and treatment. Herbert, V. Cancer (1986) [Pubmed]
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