- Apocynin improves oxygenation and increases eNOS in persistent pulmonary hypertension of the newborn. Wedgwood, S., Lakshminrusimha, S., Farrow, K.N., Czech, L., Gugino, S.F., Soares, F., Russell, J.A., Steinhorn, R.H. Am. J. Physiol. Lung Cell Mol. Physiol. (2012)