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Gene mapping of mouse laminin A and B2 subunits using mouse-Chinese hamster somatic cell hybrids.

Laminin is a multichain extracellular matrix glycoprotein found primarily in basement membranes. The molecule is made up of three subunits, designated as A, B1, and B2. Using an 850-base cDNA probe for the mouse laminin A-chain and a 1000-base cDNA probe for the mouse laminin B2 chain, we have screened mouse-Chinese hamster somatic cell hybrids in order to assign the genes for each of these polypeptides to their respective mouse chromosome. We have determined that the mouse laminin B2-chain gene is located on chromosome 1 (confirming this assignment) and the laminin A-chain gene is located on chromosome 17.[1]

References

  1. Gene mapping of mouse laminin A and B2 subunits using mouse-Chinese hamster somatic cell hybrids. Kaye, N.W., Chung, A.E., Lalley, P.A., Durkin, M.E., Phillips, S.L., Church, R.L. Somat. Cell Mol. Genet. (1990) [Pubmed]
 
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