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Gene Review

Lama1  -  laminin, alpha 1

Mus musculus

Synonyms: AA408497, Lama, Lama-1, Laminin A chain, Laminin subunit alpha-1, ...
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Disease relevance of Lama1


High impact information on Lama1


Biological context of Lama1


Anatomical context of Lama1


Associations of Lama1 with chemical compounds


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Analytical, diagnostic and therapeutic context of Lama1


  1. Modulation of murine B16F10 melanoma plasminogen activator production by a synthetic peptide derived from the laminin A chain. Stack, M.S., Gray, R.D., Pizzo, S.V. Cancer Res. (1993) [Pubmed]
  2. Increased steady-state levels of mRNA coding for extracellular matrix components in kidneys of NZB/W F1 mice. Nakamura, T., Ebihara, I., Shirato, I., Tomino, Y., Koide, H. Am. J. Pathol. (1991) [Pubmed]
  3. Angiotensin-II-induced expression of laminin complex and laminin A-chain-related transcripts in vascular smooth muscle cells. Regenass, S., Resink, T.J., Kern, F., Bühler, F.R., Hahn, A.W. J. Vasc. Res. (1994) [Pubmed]
  4. Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production. Kanemoto, T., Reich, R., Royce, L., Greatorex, D., Adler, S.H., Shiraishi, N., Martin, G.R., Yamada, Y., Kleinman, H.K. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  5. Monoclonal antibodies against laminin A chain fragment E3 and their effects on binding to cells and proteoglycan and on kidney development. Sorokin, L.M., Conzelmann, S., Ekblom, P., Battaglia, C., Aumailley, M., Timpl, R. Exp. Cell Res. (1992) [Pubmed]
  6. Transient and locally restricted expression of laminin A chain mRNA by developing epithelial cells during kidney organogenesis. Ekblom, M., Klein, G., Mugrauer, G., Fecker, L., Deutzmann, R., Timpl, R., Ekblom, P. Cell (1990) [Pubmed]
  7. Recognition of the laminin E8 cell-binding site by an integrin possessing the alpha 6 subunit is essential for epithelial polarization in developing kidney tubules. Sorokin, L., Sonnenberg, A., Aumailley, M., Timpl, R., Ekblom, P. J. Cell Biol. (1990) [Pubmed]
  8. Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation. Miner, J.H., Li, C., Mudd, J.L., Go, G., Sutherland, A.E. Development (2004) [Pubmed]
  9. SOX7 and SOX17 regulate the parietal endoderm-specific enhancer activity of mouse laminin alpha1 gene. Niimi, T., Hayashi, Y., Futaki, S., Sekiguchi, K. J. Biol. Chem. (2004) [Pubmed]
  10. Kruppel-like factors regulate the Lama1 gene encoding the laminin alpha1 chain. Piccinni, S.A., Bolcato-Bellemin, A.L., Klein, A., Yang, V.W., Kedinger, M., Simon-Assmann, P., Lefebvre, O. J. Biol. Chem. (2004) [Pubmed]
  11. Sequence of extracellular mouse protein BM-90/fibulin and its calcium-dependent binding to other basement-membrane ligands. Pan, T.C., Kluge, M., Zhang, R.Z., Mayer, U., Timpl, R., Chu, M.L. Eur. J. Biochem. (1993) [Pubmed]
  12. Gene mapping of mouse laminin A and B2 subunits using mouse-Chinese hamster somatic cell hybrids. Kaye, N.W., Chung, A.E., Lalley, P.A., Durkin, M.E., Phillips, S.L., Church, R.L. Somat. Cell Mol. Genet. (1990) [Pubmed]
  13. Differential expression of laminin A and B chains during development of embryonic mouse organs. Klein, G., Ekblom, M., Fecker, L., Timpl, R., Ekblom, P. Development (1990) [Pubmed]
  14. The RGD containing site of the mouse laminin A chain is active for cell attachment, spreading, migration and neurite outgrowth. Tashiro, K., Sephel, G.C., Greatorex, D., Sasaki, M., Shirashi, N., Martin, G.R., Kleinman, H.K., Yamada, Y. J. Cell. Physiol. (1991) [Pubmed]
  15. Differences in cell surface carbohydrates, and in laminin and fibronectin synthesis, between adherent and non-adherent Ehrlich ascites tumor cells. Song, Z., Varani, J., Goldstein, I.J. Int. J. Cancer (1993) [Pubmed]
  16. Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine. Simon-Assmann, P., Duclos, B., Orian-Rousseau, V., Arnold, C., Mathelin, C., Engvall, E., Kedinger, M. Dev. Dyn. (1994) [Pubmed]
  17. Mast cells chemotax to laminin with enhancement after IgE-mediated activation. Thompson, H.L., Burbelo, P.D., Yamada, Y., Kleinman, H.K., Metcalfe, D.D. J. Immunol. (1989) [Pubmed]
  18. Expression of laminin chain-specific gene transcripts in mouse uterine tissues during peri-implantation period. Shim, C., Choi, D., Kwon, H.B., Kim, K. Mol. Reprod. Dev. (1997) [Pubmed]
  19. The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule. Noonan, D.M., Fulle, A., Valente, P., Cai, S., Horigan, E., Sasaki, M., Yamada, Y., Hassell, J.R. J. Biol. Chem. (1991) [Pubmed]
  20. Tissue-specific expression in the salivary glands of transgenic mice. Mikkelsen, T.R., Brandt, J., Larsen, H.J., Larsen, B.B., Poulsen, K., Ingerslev, J., Din, N., Hjorth, J.P. Nucleic Acids Res. (1992) [Pubmed]
  21. Immune response of the llama (Lama glama) to tetanus toxoid vaccination. Paul-Murphy, J., Gershwin, L.J., Thatcher, E.F., Fowler, M.E., Habig, W.H. Am. J. Vet. Res. (1989) [Pubmed]
  22. Lama glama (the South American camelid, llama): a unique model for evaluation of xenogenic islet transplants in a cerebral spinal fluid driven artificial organ. Ommaya, A.K., Atwater, I., Yañez, A., Szpak-Glasman, M., Bacher, J., Arriaza, C., Baer, L., Parraguez, V., Navia, A., Oberti, C. Transplant. Proc. (1995) [Pubmed]
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