Histologic and statistical studies on hyalin bodies in the human endolymphatic sac.
Hyalin bodies are amorphous, eosinophilic masses that protrude from the subepithelial connective tissue into the lumen of the endolymphatic sac. In this study, hyalin bodies were analyzed in two groups of temporal bones: normal bones and bones with cochlear otosclerosis. The results revealed that bones with cochlear otosclerosis had significantly more and larger hyalin bodies that did normal bones. In addition, the hyalin bodies in cochlear otosclerosis were denser and associated with more edema and loose connective tissue in the surrounding areas. Foamy macrophages, concentric calcific structures, and bony ingrowth were frequent features of the hyalin bodies in the cochlear otosclerosis. Our current hypothesis is that these hyalin bodies are repository of membranous cellular debris phagocytized by the macrophages. If this is true, the hyalin bodies may further support the proposed resorptive and phagocytic functions of the endolymphatic sac and the enzymatic concept in cochlear otosclerosis.[1]References
- Histologic and statistical studies on hyalin bodies in the human endolymphatic sac. Bui, H.T., Linthicum, F.H. The American journal of otology. (1989) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
