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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni.

AIMS: Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence. MATERIALS AND METHODS: Dental patients who received amlodipine (N = 115), for more than 3 months were studied to determine the drug-induced gingival overgrowth. Clinical diagnosis of drug-induced overgrowth was verified by disappearance or decreased severity of gingival overgrowth after withdrawal of the causative drug. RESULTS: The prevalence rate of amlodipine-induced gingival hyperplasia among experimental patients was 3.4%, while it was not observed among the control subjects. Oral examination revealed gingival overgrowth as a lobular or nodular enlargement on interdental papilla located in the anterior interproximal regions. CONCLUSIONS: In this study, there was a significant relationship between gingival inflammation resulting from dental plaque and drug dosage, and hyperplasia.[1]

References

  1. Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni. Tejnani, A., Mani, A., Sodhi, N.K., Mehta, A., Gourkhede, S., Thorat, V., Marawar, P. J. Indian. Soc. Periodontol (2014) [Pubmed]
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