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MeSH Review

Gingival Overgrowth

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Disease relevance of Gingival Overgrowth


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Chemical compound and disease context of Gingival Overgrowth


Biological context of Gingival Overgrowth


Anatomical context of Gingival Overgrowth


Gene context of Gingival Overgrowth


Analytical, diagnostic and therapeutic context of Gingival Overgrowth


  1. Medically induced gingival hyperplasia. Meraw, S.J., Sheridan, P.J. Mayo Clin. Proc. (1998) [Pubmed]
  2. Interactive Grand Rounds. Case 3: management of cyclosporine-induced hirsutism and gingival overgrowth in a heart transplant recipient. Rosario, A.M., Young, J.B. J. Heart Lung Transplant. (2000) [Pubmed]
  3. Factors related to the incidence and severity of cyclosporin-induced gingival overgrowth in transplant patients. A longitudinal study. Somacarrera, M.L., Hernández, G., Acero, J., Moskow, B.S. J. Periodontol. (1994) [Pubmed]
  4. Expression of RNAs encoding for alpha and beta integrin subunits in periodontitis and in cyclosporin A gingival overgrowth. Bolcato-Bellemin, A.L., Elkaim, R., Tenenbaum, H. Journal of clinical periodontology. (2003) [Pubmed]
  5. Post-transplant lymphoproliferative disorders presenting as gingival overgrowth in patients immunosuppressed with ciclosporin. A report of two cases. Rolland, S.L., Seymour, R.A., Wilkins, B.S., Parry, G., Thomason, J.M. Journal of clinical periodontology. (2004) [Pubmed]
  6. Gingival sequestration of amlodipine and amlodipine-induced gingival overgrowth. Ellis, J.S., Seymour, R.A., Thomason, J.M., Monkman, S.C., Idle, J.R. Lancet (1993) [Pubmed]
  7. Gingival sequestration of nifedipine in nifedipine-induced gingival overgrowth. Ellis, J.S., Seymour, R.A., Monkman, S.C., Idle, J.R. Lancet (1992) [Pubmed]
  8. Diphenylhydantoin (dilantin) gingival hyperplasia: drug-induced abnormality of connective tissue. Hassell, T.M., Page, R.C., Narayanan, A.S., Cooper, C.G. Proc. Natl. Acad. Sci. U.S.A. (1976) [Pubmed]
  9. Cathepsin-L, a key molecule in the pathogenesis of drug-induced and I-cell disease-mediated gingival overgrowth: a study with cathepsin-L-deficient mice. Nishimura, F., Naruishi, H., Naruishi, K., Yamada, T., Sasaki, J., Peters, C., Uchiyama, Y., Murayama, Y. Am. J. Pathol. (2002) [Pubmed]
  10. Risk factors in the development of cyclosporine-induced gingival overgrowth. Thomas, D.W., Newcombe, R.G., Osborne, G.R. Transplantation (2000) [Pubmed]
  11. Alpha 2 integrin +807 polymorphism in drug-induced gingival overgrowth. Ogino, M., Kido, J., Bando, M., Hayashi, N., Wada, C., Nagata, T., Nishimura, F., Soga, Y., Takashiba, S., Kubota, T., Itagaki, M., Shimada, Y., Tai, H., Yoshie, H., Yamazaki, N., Shinohara, Y., Kataoka, M. J. Dent. Res. (2005) [Pubmed]
  12. The use of azithromycin for cyclosporin-induced gingival overgrowth. Jucglà, A., Moreso, F., Sais, G., Gil-Vernet, S., Graells, J., Grinyó, J.M., Peyrí, J. Br. J. Dermatol. (1998) [Pubmed]
  13. Gingival overgrowth among renal transplant recipients and uraemic patients. Pernu, H.E., Pernu, L.M., Knuuttila, M.L., Huttunen, K.R. Nephrol. Dial. Transplant. (1993) [Pubmed]
  14. Inhibition by tranilast of nifedipine-induced proliferation of cultured human gingival fibroblasts. Hattori, T., Wang, P.L. Eur. J. Pharmacol. (2004) [Pubmed]
  15. The immunosuppressant and hyperplasia-inducing drug cyclosporin A regulates the cell cycle and cyclin B1 gene expression in gingival fibroblasts in vitro. Parkar, M.H., Hussain, F., Wickramaratna, A., Olsen, I. Cell Tissue Res. (2004) [Pubmed]
  16. The influence of transforming growth factor-beta1 gene polymorphisms on the severity of gingival overgrowth associated with concomitant use of cyclosporin A and a calcium channel blocker. Linden, G.J., Haworth, S.E., Maxwell, A.P., Poulton, K.V., Dyer, P.A., Middleton, D., Irwin, C.R., Marley, J.J., McNamee, P., Short, C.D., Hull, P.S., James, J.A. J. Periodontol. (2001) [Pubmed]
  17. Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor gene and protein expression in cyclosporin-induced overgrown edentulous gingiva in rats. Chen, Y.T., Tu, H.P., Chin, Y.T., Shen, E.C., Chiang, C.Y., Gau, C.H., Fu, E. J. Periodontol. (2005) [Pubmed]
  18. Upregulation of keratinocyte growth factor in cyclosporin A-induced gingival overgrowth. Das, S.J., Parkar, M.H., Olsen, I. J. Periodontol. (2001) [Pubmed]
  19. Apoptosis in cyclosporin A-induced gingival overgrowth: a histological study. Alaaddinoglu, E.E., Karabay, G., Bulut, S., Oduncuoglu, F.B., Ozdemir, H., Bulut, O.E., Colak, T. J. Periodontol. (2005) [Pubmed]
  20. Inhibition by nifedipine of adherence- and activated macrophage-induced death of human gingival fibroblasts. Fujimori, Y., Maeda, S., Saeki, M., Morisaki, I., Kamisaki, Y. Eur. J. Pharmacol. (2001) [Pubmed]
  21. A quantitative analysis of connective tissue components in phenytoin-induced gingival overgrowth in children. A stereological study. Dahllöf, G., Reinholt, F.P., Hjerpe, A., Modéer, T. J. Periodont. Res. (1984) [Pubmed]
  22. Cyclosporin A regulates interleukin-1beta and interleukin-6 expression in gingiva: implications for gingival overgrowth. Myrillas, T.T., Linden, G.J., Marley, J.J., Irwin, C.R. J. Periodontol. (1999) [Pubmed]
  23. Mitotic activity of keratinocytes in nifedipine- and immunosuppressive medication-induced gingival overgrowth. Nurmenniemi, P.K., Pernu, H.E., Knuuttila, M.L. J. Periodontol. (2001) [Pubmed]
  24. Density of CD1a-labeled Langerhans' cells in normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth. Nurmenniemi, P.K., Pernu, H.E., Knuuttila, M.L. J. Periodontol. (1999) [Pubmed]
  25. TGF-beta isoforms and TGF-beta receptors in drug-induced and hereditary gingival overgrowth. Wright, H.J., Chapple, I.L., Matthews, J.B. J. Oral Pathol. Med. (2001) [Pubmed]
  26. Connective tissue growth factor in drug-induced gingival overgrowth. Uzel, M.I., Kantarci, A., Hong, H.H., Uygur, C., Sheff, M.C., Firatli, E., Trackman, P.C. J. Periodontol. (2001) [Pubmed]
  27. Upregulation of the expression of epidermal growth factor and its receptor in gingiva upon cyclosporin a treatment. Chin, Y.T., Chen, Y.T., Tu, H.P., Shen, E.C., Chiang, C.Y., Gau, C.H., Nieh, S., Fu, E. J. Periodontol. (2006) [Pubmed]
  28. Decreased expressions of thrombospondin 2 in cyclosporin A-induced gingival overgrowth. Koh, J.T., Kim, O.J., Park, Y.S., Kim, S.H., Kim, W.J., Chung, H.J., Lee, S.E., Jeong, B.C., Jung, J.Y., Kim, K.K. J. Periodont. Res. (2004) [Pubmed]
  29. Plasminogen activators and plasminogen activator inhibitors in gingival crevicular fluid of cyclosporin A-treated patients. Buduneli, N., Buduneli, E., Ciotanar, S., Atilla, G., Lappin, D., Kinane, D. Journal of clinical periodontology. (2004) [Pubmed]
  30. Gingival overgrowth in pediatric heart and heart-lung transplant recipients. Kilpatrick, N.M., Weintraub, R.G., Lucas, J.O., Shipp, A., Byrt, T., Wilkinson, J.L. J. Heart Lung Transplant. (1997) [Pubmed]
  31. Determinants of gingival overgrowth severity in organ transplant patients. An examination of the rôle of HLA phenotype. Thomason, J.M., Seymour, R.A., Ellis, J.S., Kelly, P.J., Parry, G., Dark, J., Wilkinson, R., Ilde, J.R. Journal of clinical periodontology. (1996) [Pubmed]
  32. Phenytoin-induced gingival overgrowth: a community-based cross-sectional study in Ferrara, Italy. Casetta, I., Granieri, E., Desiderá, M., Monetti, V.C., Tola, M.R., Paolino, E., Govoni, V., Calura, G. Neuroepidemiology. (1997) [Pubmed]
  33. Severe gingival overgrowth associated with cyclosporine therapy. Rostock, M.H., Fry, H.R., Turner, J.E. J. Periodontol. (1986) [Pubmed]
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