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Epidural meperidine for control of autonomic hyperreflexia in a quadriplegic undergoing cystoscopy.

Epidural meperidine was used to control autonomic hyperreflexia (AH) during cystoscopy and transuretheral sphincterotomy, in a quadriplegic patient who had chronic spinal cord transection at C6 level. Meperidine 100 mg diluted in 10 ml saline was injected in the epidural space at L3-L4 level. Within 10 minutes and throughout the surgical procedure, the blood pressure stabilized at 125/70-140/80 mmHg. Epidural meperidine produces selective blockade of the spinal opiate receptors and hence may block the nociceptive reflexes below the level of cord transection and prevent AH.[1]

References

  1. Epidural meperidine for control of autonomic hyperreflexia in a quadriplegic undergoing cystoscopy. Baraka, A., Noueihid, R., Sibai, A.N., Baroody, M., Louis, F., Hemady, K. Middle East journal of anesthesiology. (1989) [Pubmed]
 
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