The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

HRX  -  Hyperreflexia

Homo sapiens

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of HRX

 

Psychiatry related information on HRX

 

High impact information on HRX

 

Chemical compound and disease context of HRX

 

Biological context of HRX

 

Anatomical context of HRX

 

Associations of HRX with chemical compounds

  • Although no single sign distinguished the groups, patients with mutations had significantly earlier and more symmetrical onset, dystonia more often at onset and hyperreflexia, slower progression of the disease, and a tendency toward a greater response to levodopa despite lower doses [30].
  • In 2 controlled trials, there was no significant difference between dantrolene and diazepam in terms of reductions in spasticity, clonus, and hyperreflexia, but side-effects such as drowsiness and inco-ordination occurred significantly more frequently on diazepam [31].
  • EMDA of oxybutynin reduced detrusor hyperreflexia [32].
  • The use of intravesical oxybutynin chloride in patients with detrusor hypertonicity and detrusor hyperreflexia [33].
  • A calcium blocking and anticholinergic agent (terodiline) in the treatment of detrusor hyperreflexia: a placebo-controlled, cross-over trial [34].
 

Regulatory relationships of HRX

 

Other interactions of HRX

 

Analytical, diagnostic and therapeutic context of HRX

References

  1. Detrusor hyperactivity with impaired contractile function. An unrecognized but common cause of incontinence in elderly patients. Resnick, N.M., Yalla, S.V. JAMA (1987) [Pubmed]
  2. High-dose oral tamoxifen, a potential multidrug-resistance-reversal agent: phase I trial in combination with vinblastine. Trump, D.L., Smith, D.C., Ellis, P.G., Rogers, M.P., Schold, S.C., Winer, E.P., Panella, T.J., Jordan, V.C., Fine, R.L. J. Natl. Cancer Inst. (1992) [Pubmed]
  3. Treatment of refractory urge urinary incontinence with sacral spinal nerve stimulation in multiple sclerosis patients. Ruud Bosch, J.L., Groen, J. Lancet (1996) [Pubmed]
  4. Idiopathic hemiparetic parkinsonism, a syndrome distinct from idiopathic parkinsonism. De Keyser, J., Herroelen, L., Vervaeck, M., Bruyland, M., Ebinger, G. Lancet (1992) [Pubmed]
  5. Acute anticholinergic syndrome due to Jimson seed ingestion. Clinical and laboratory observation in six cases. Mikolich, J.R., Paulson, G.W., Cross, C.J. Ann. Intern. Med. (1975) [Pubmed]
  6. Allan-Herndon syndrome. I. Clinical studies. Stevenson, R.E., Goodman, H.O., Schwartz, C.E., Simensen, R.J., McLean, W.T., Herndon, C.N. Am. J. Hum. Genet. (1990) [Pubmed]
  7. Benign autosomal dominant syndrome of neuronal Charcot-Marie-Tooth disease, ptosis, parkinsonism, and dementia. Tandan, R., Taylor, R., Adesina, A., Sharma, K., Fries, T., Pendlebury, W. Neurology (1990) [Pubmed]
  8. Cortical-basal ganglionic degeneration. Riley, D.E., Lang, A.E., Lewis, A., Resch, L., Ashby, P., Hornykiewicz, O., Black, S. Neurology (1990) [Pubmed]
  9. Precocious aging and dementia in patients with Down's syndrome. Wisniewski, K., Howe, J., Williams, D.G., Wisniewski, H.M. Biol. Psychiatry (1978) [Pubmed]
  10. Selective serotonin reuptake inhibitor-induced serotonin syndrome: review. Lane, R., Baldwin, D. Journal of clinical psychopharmacology. (1997) [Pubmed]
  11. Identification and expression analysis of spastin gene mutations in hereditary spastic paraplegia. Svenson, I.K., Ashley-Koch, A.E., Gaskell, P.C., Riney, T.J., Cumming, W.J., Kingston, H.M., Hogan, E.L., Boustany, R.M., Vance, J.M., Nance, M.A., Pericak-Vance, M.A., Marchuk, D.A. Am. J. Hum. Genet. (2001) [Pubmed]
  12. Prospective assessment of risks for cervicomedullary-junction compression in infants with achondroplasia. Pauli, R.M., Horton, V.K., Glinski, L.P., Reiser, C.A. Am. J. Hum. Genet. (1995) [Pubmed]
  13. Etiological heterogeneity in X-linked spastic paraplegia. Keppen, L.D., Leppert, M.F., O'Connell, P., Nakamura, Y., Stauffer, D., Lathrop, M., Lalouel, J.M., White, R. Am. J. Hum. Genet. (1987) [Pubmed]
  14. Bladder afferent pathway and spinal cord injury: possible mechanisms inducing hyperreflexia of the urinary bladder. Yoshimura, N. Prog. Neurobiol. (1999) [Pubmed]
  15. Fulminant hepatic failure after repeated exposure to isoflurane anesthesia: a case report. Brunt, E.M., White, H., Marsh, J.W., Holtmann, B., Peters, M.G. Hepatology (1991) [Pubmed]
  16. Current perspectives on the therapeutic utility of VR1 antagonists. Valenzano, K.J., Sun, Q. Current medicinal chemistry. (2004) [Pubmed]
  17. Phenelzine toxicity responsive to dantrolene. Verrilli, M.R., Salanga, V.D., Kozachuk, W.E., Bennetts, M. Neurology (1987) [Pubmed]
  18. Serotonin syndrome. Bodner, R.A., Lynch, T., Lewis, L., Kahn, D. Neurology (1995) [Pubmed]
  19. Nicotine-sensitive paresis. Yokota, T., Kagamihara, Y., Hayashi, H., Tsukagoshi, H., Tanabe, H. Neurology (1992) [Pubmed]
  20. Causes of urinary incontinence after acute hemispheric stroke. Gelber, D.A., Good, D.C., Laven, L.J., Verhulst, S.J. Stroke (1993) [Pubmed]
  21. Acute carbamazepine toxicity resulting from overdose. Sullivan, J.B., Rumack, B.H., Peterson, R.G. Neurology (1981) [Pubmed]
  22. Pressor dose responses and baroreflex sensitivity in quadriplegic spinal cord injury patients. Krum, H., Louis, W.J., Brown, D.J., Howes, L.G. J. Hypertens. (1992) [Pubmed]
  23. Oculomotor, auditory, and vestibular responses in myotonic dystrophy. Verhagen, W.I., ter Bruggen, J.P., Huygen, P.L. Arch. Neurol. (1992) [Pubmed]
  24. Acute and delayed transplantation of olfactory ensheathing cells promote partial recovery after complete transection of the spinal cord. López-Vales, R., Forés, J., Verdú, E., Navarro, X. Neurobiol. Dis. (2006) [Pubmed]
  25. Regional metabolic changes in the spinal cord related to spinal shock and later hyperreflexia in monkeys. Schwartzman, R.J., Eidelberg, E., Alexander, G.M., Yu, J. Ann. Neurol. (1983) [Pubmed]
  26. Primary amyloidosis with peripheral neuropathy and signs of motor neuron disease. Abarbanel, J.M., Frisher, S., Osimani, A. Neurology (1986) [Pubmed]
  27. Prediagnostic human T lymphotropic virus type I provirus loads were highest in Jamaican children who developed seborrheic dermatitis and severe anemia. Maloney, E.M., Nagai, M., Hisada, M., Soldan, S.S., Goebel, P.B., Carrington, M., Sawada, T., Brennan, M.B., Cranston, B., Hanchard, B., Jacobson, S. J. Infect. Dis. (2004) [Pubmed]
  28. Treatment of lower urinary tract dysfunction in patients with multiple sclerosis. Committee of the European Study Group of SUDIMS (Sexual and Urological Disorders in Multiple Sclerosis). Fowler, C.J., van Kerrebroeck, P.E., Nordenbo, A., Van Poppel, H. J. Neurol. Neurosurg. Psychiatr. (1992) [Pubmed]
  29. Central motor conduction studies in hereditary spastic paraplegia. Schady, W., Dick, J.P., Sheard, A., Crampton, S. J. Neurol. Neurosurg. Psychiatr. (1991) [Pubmed]
  30. How much phenotypic variation can be attributed to parkin genotype? Lohmann, E., Periquet, M., Bonifati, V., Wood, N.W., De Michele, G., Bonnet, A.M., Fraix, V., Broussolle, E., Horstink, M.W., Vidailhet, M., Verpillat, P., Gasser, T., Nicholl, D., Teive, H., Raskin, S., Rascol, O., Destée, A., Ruberg, M., Gasparini, F., Meco, G., Agid, Y., Durr, A., Brice, A. Ann. Neurol. (2003) [Pubmed]
  31. Dantrolene sodium: a review of its pharmacological properties and therapeutic efficacy in spasticity. Pinder, R.M., Brogden, R.N., Speight, T.M., Avery, G.S. Drugs (1977) [Pubmed]
  32. Intravesical electromotive drug administration technique: preliminary results and side effects. Riedl, C.R., Knoll, M., Plas, E., Pflüger, H. J. Urol. (1998) [Pubmed]
  33. The use of intravesical oxybutynin chloride in patients with detrusor hypertonicity and detrusor hyperreflexia. Kasabian, N.G., Vlachiotis, J.D., Lais, A., Klumpp, B., Kelly, M.D., Siroky, M.B., Bauer, S.B. J. Urol. (1994) [Pubmed]
  34. A calcium blocking and anticholinergic agent (terodiline) in the treatment of detrusor hyperreflexia: a placebo-controlled, cross-over trial. Petersen, T., Jakobsen, J. J. Neurol. Neurosurg. Psychiatr. (1987) [Pubmed]
  35. Effects of selective beta2 and beta3-adrenoceptor agonists on detrusor hyperreflexia in conscious cerebral infarcted rats. Kaidoh, K., Igawa, Y., Takeda, H., Yamazaki, Y., Akahane, S., Miyata, H., Ajisawa, Y., Nishizawa, O., Andersson, K.E. J. Urol. (2002) [Pubmed]
  36. Corticotropin-releasing factor modulates cardiovascular and pupillary autonomic reflexes in man: is there a link to inflammation-induced autonomic nervous hyperreflexia? Pongratz, G., Zietz, B., Glück, T., Schölmerich, J., Straub, R.H. Ann. N. Y. Acad. Sci. (2002) [Pubmed]
  37. Activity of nonpeptide tachykinin antagonists on neurokinin a induced contractions in dog urinary bladder. Rizzo, C.A., Hey, J.A. J. Urol. (2000) [Pubmed]
  38. Corticospinal tract involvement in a variant of Guillain-Barré syndrome. Oshima, Y., Mitsui, T., Endo, I., Umaki, Y., Matsumoto, T. Eur. Neurol. (2001) [Pubmed]
  39. Neuropathic bladder dysfunction in patients with ossification of the posterior longitudinal ligament. Miyata, M., Mizunaga, M., Taniguchi, N., Kaneko, S., Yachiku, S., Atsuta, Y. International journal of urology : official journal of the Japanese Urological Association. (1998) [Pubmed]
  40. Autosomal dominant, familial spastic paraplegia, type I: clinical and genetic analysis of a large North American family. Fink, J.K., Sharp, G.B., Lange, B.M., Wu, C.B., Haley, T., Otterud, B., Peacock, M., Leppert, M. Neurology (1995) [Pubmed]
  41. Micturitional disturbance in pure autonomic failure. Sakakibara, R., Hattori, T., Uchiyama, T., Asahina, M., Yamanishi, T. Neurology (2000) [Pubmed]
  42. Catheter-induced hyperreflexia in spinal cord injury patients: diagnosis by sonographic voiding cystourethrography. Perkash, I., Friedland, G.W. Radiology. (1986) [Pubmed]
  43. Urodynamic effects of intravesical resiniferatoxin in humans: preliminary results in stable and unstable detrusor. Lazzeri, M., Beneforti, P., Turini, D. J. Urol. (1997) [Pubmed]
 
WikiGenes - Universities