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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Comparative in vitro antimicrobial activity of carumonam, a new monocyclic beta-lactam.

The antimicrobial activity of carumonam (formerly RO-17-2301), a monocyclic beta-lactam antibiotic, was compared with those of aztreonam, cefotaxime, cefoperazone, ceftazidime, piperacillin, and gentamicin against 455 bacterial isolates. Carumonam did not possess activity against gram-positive cocci and was generally comparable to aztreonam and ceftazidime for most gram-negative bacilli. However, carumonam was the most active beta-lactam against gentamicin-resistant Pseudomonas aeruginosa strains (90% MIC, 8 micrograms/ml).[1]

References

  1. Comparative in vitro antimicrobial activity of carumonam, a new monocyclic beta-lactam. Smith, B.R., LeFrock, J.L., McCloskey, R.V., Donato, J.B., Weber, S.J., Joseph, W.S. Antimicrob. Agents Chemother. (1986) [Pubmed]
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