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Chemical Compound Review

Cefobid     (6R,7S)-7-[[(2R)-2-[(4-ethyl- 2,3-dioxo...

Synonyms: Cefozon, Medocef, Cefob, Cefoperazine, Cefoperazono, ...
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Disease relevance of CEFONICID


High impact information on CEFONICID


Chemical compound and disease context of CEFONICID


Biological context of CEFONICID


Anatomical context of CEFONICID


Associations of CEFONICID with other chemical compounds


Gene context of CEFONICID


Analytical, diagnostic and therapeutic context of CEFONICID


  1. Treatment of late Lyme borreliosis with cefoperazone and sulbactam. Gasser, R.N., Reisinger, E.C., Eber, B., Wendelin, I., Pokan, R., Seinost, G., Klein, W. Lancet (1995) [Pubmed]
  2. Hypoprothrombinemia and bleeding due to cefoperazone. Osborne, J.C. Ann. Intern. Med. (1985) [Pubmed]
  3. Comparative in vitro activities of third-generation cephalosporins. Fass, R.J. Arch. Intern. Med. (1983) [Pubmed]
  4. Cefoperazone plus tobramycin versus ticarcillin plus tobramycin in febrile granulocytopenic cancer patients. Gucalp, R., Lia, S., McKitrick, J.C., Wiernik, P.H. Am. J. Med. (1988) [Pubmed]
  5. In vitro activities of cefoperazone and sulbactam singly and in combination against cefoperazone-resistant members of the family Enterobacteriaceae and nonfermenters. Fass, R.J., Gregory, W.W., D'Amato, R.F., Matsen, J.M., Wright, D.N., Young, L.S. Antimicrob. Agents Chemother. (1990) [Pubmed]
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  7. Reversal by cefoperazone of resistance to etoposide, doxorubicin, and vinblastine in multidrug resistant human sarcoma cells. Gosland, M.P., Lum, B.L., Sikic, B.I. Cancer Res. (1989) [Pubmed]
  8. Clinical applications of a new parenteral antibiotic in the treatment of severe bacterial infections. Holloway, W.J., Palmer, D. Am. J. Med. (1996) [Pubmed]
  9. Cefoperazone plus piperacillin versus mezlocillin plus tobramycin as empiric therapy for febrile episodes in neutropenic patients. Rotstein, C., Cimino, M., Winkey, K., Cesari, C., Fenner, J. Am. J. Med. (1988) [Pubmed]
  10. In vitro susceptibility of gram-negative bacilli from pediatric patients to moxalactam, cefotaxime, Ro 13-9904, and other cephalosporins. Shelton, S., Nelson, J.D., McCracken, G.H. Antimicrob. Agents Chemother. (1980) [Pubmed]
  11. Inoculum effect of beta-lactam antibiotics on Enterobacteriaceae. Eng, R.H., Cherubin, C., Smith, S.M., Buccini, F. Antimicrob. Agents Chemother. (1985) [Pubmed]
  12. In vitro activity of azthreonam, a monobactam antibiotic. Jacobus, N.V., Ferreira, M.C., Barza, M. Antimicrob. Agents Chemother. (1982) [Pubmed]
  13. Influence of inoculum size on activity of cefoperazone, cefotaxime, moxalactam, piperacillin, and N-formimidoyl thienamycin (MK0787) against Pseudomonas aeruginosa. Corrado, M.L., Landesman, S.H., Cherubin, C.E. Antimicrob. Agents Chemother. (1980) [Pubmed]
  14. Susceptibilities of anaerobic bacteria to cefoperazone and other antibiotics. Kaye, D., Kobasa, W., Kaye, K. Antimicrob. Agents Chemother. (1980) [Pubmed]
  15. Affinity of cefmenoxime for beta-lactamases: an analysis. Labia, R., Morand, A., Verchere-Beaur, C., Bryskier, A. Am. J. Med. (1984) [Pubmed]
  16. Intraperitoneal and intravenous cefoperazone kinetics during continuous ambulatory peritoneal dialysis. Keller, E., Jansen, A., Pelz, K., Hoppe-Seyler, G., Schollmeyer, P. Clin. Pharmacol. Ther. (1984) [Pubmed]
  17. Multiple-dose pharmacokinetics of intravenously administered cefoperazone and sulbactam when given in combination to infected, seriously ill, elderly patients. Schwartz, J.I., Jauregui, L.E., Bachmann, K.A., Martin, M.E., Reitberg, D.P. Antimicrob. Agents Chemother. (1988) [Pubmed]
  18. Pharmacokinetics and pharmacodynamics of cefoperazone-sulbactam in patients on continuous ambulatory peritoneal dialysis. Johnson, C.A., Zimmerman, S.W., Reitberg, D.P., Whall, T.J., Leggett, J.E., Craig, W.A. Antimicrob. Agents Chemother. (1988) [Pubmed]
  19. Diffusibility of the newer cephalosporins into human interstitial fluids. Tan, J.S., Salstrom, S.J., File, T.M. Am. J. Med. (1984) [Pubmed]
  20. Serum and urine concentrations of cefoperazone in severe chronic renal failure. Bailey, R.R., Peddie, B., Blake, E. Drugs (1981) [Pubmed]
  21. Cefoperazone in Klebsiella meningitis: a case report. Ellis-Pegler, R.B., Lang, S.D. Drugs (1981) [Pubmed]
  22. Clinical experience with cefoperazone in biliary tract infections. Mashimo, K. Drugs (1981) [Pubmed]
  23. Effect of broad-spectrum parenteral antibiotics on composition of intestinal microflora of humans. Giuliano, M., Barza, M., Jacobus, N.V., Gorbach, S.L. Antimicrob. Agents Chemother. (1987) [Pubmed]
  24. Review of in vitro activity of third-generation cephalosporins and other newer beta-lactam antibiotics against clinically important bacteria. Thornsberry, C. Am. J. Med. (1985) [Pubmed]
  25. Comparative pharmacokinetics of cefoperazone, cefotaxime, and moxalactam. Kemmerich, B., Lode, H., Belmega, G., Jendroschek, T., Borner, K., Koeppe, P. Antimicrob. Agents Chemother. (1983) [Pubmed]
  26. Effects of broad-spectrum antimicrobial agents on yeast colonization of the gastrointestinal tracts of mice. Samonis, G., Anaissie, E.J., Bodey, G.P. Antimicrob. Agents Chemother. (1990) [Pubmed]
  27. Diffusion of beta-lactam antibiotics through the porin channels of Escherichia coli K-12. Yoshimura, F., Nikaido, H. Antimicrob. Agents Chemother. (1985) [Pubmed]
  28. Comparative pharmacokinetics of cefoperazone and cefamandole. Srinivasan, S., Francke, E.L., Neu, H.C. Antimicrob. Agents Chemother. (1981) [Pubmed]
  29. In vitro antimicrobial activity of cefoperazone-sulbactam combinations against 554 clinical isolates including a review and beta-lactamase studies. Jones, R.N., Wilson, H.W., Thornsberry, C., Barry, A.L. Diagn. Microbiol. Infect. Dis. (1985) [Pubmed]
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  32. Comparative study of cefoperazone and spectinomycin for treatment of uncomplicated gonorrhea in men. Hook, E.W., Judson, F.N., Verdon, M.S., Ehret, J.M., Handsfield, H.H. Antimicrob. Agents Chemother. (1986) [Pubmed]
  33. In vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporin. Matsubara, N., Minami, S., Muraoka, T., Saikawa, I., Mitsuhashi, S. Antimicrob. Agents Chemother. (1979) [Pubmed]
  34. Cefoperazone pharmacokinetics in normal subjects and patients with cirrhosis. Boscia, J.A., Korzeniowski, O.M., Snepar, R., Kobasa, W.D., Levison, M.E., Kaye, D. Antimicrob. Agents Chemother. (1983) [Pubmed]
  35. Worldwide clinical experience with cefoperazone. Gerber, A.U., Craig, W.A. Drugs (1981) [Pubmed]
  36. Pharmacokinetics of cefoperazone (2.0 g) and sulbactam (1.0 g) coadministered to subjects with normal renal function, patients with decreased renal function, and patients with end-stage renal disease on hemodialysis. Reitberg, D.P., Marble, D.A., Schultz, R.W., Whall, T.J., Schentag, J.J. Antimicrob. Agents Chemother. (1988) [Pubmed]
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