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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Antifungal activity of fenticonazole in experimental dermatomycosis and candidiasis.

The antifungal activity of alpha-(2,4-dichlorophenyl)-beta,N-imidazolylethyl 4-phenylthiobenzyl ether nitrate (fenticonazole, Rec 15/1476) in experimental dermatomycosis and candidiasis in guinea pigs was studied. Fenticonazole proved to be a very active drug with a healing capacity generally higher than that of the reference compounds. The adequate range of activity was from 1% to 3%, giving complete healing without relapses in 100% of cases treated. Fenticonazole is presently undergoing further experimental studies and on the basis of our results a clinical trial would therefore seem to be essential.[1]

References

  1. Antifungal activity of fenticonazole in experimental dermatomycosis and candidiasis. Veronese, M., Barzaghi, D., Bertoncini, A. Arzneimittel-Forschung. (1981) [Pubmed]
 
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