- Brucella abortus conjugated with a gp120 or V3 loop peptide derived from human immunodeficiency virus (HIV) type 1 induces neutralizing anti-HIV antibodies, and the V3-B. abortus conjugate is effective even after CD4+ T-cell depletion. Golding, B., Inman, J., Highet, P., Blackburn, R., Manischewitz, J., Blyveis, N., Angus, R.D., Golding, H. J. Virol. (1995)